6hrl: Difference between revisions
From Proteopedia
Jump to navigationJump to search
m Protected "6hrl" [edit=sysop:move=sysop] |
No edit summary |
||
| Line 1: | Line 1: | ||
==Crystal structure of the Kelch domain of human KLHL17== | |||
<StructureSection load='6hrl' size='340' side='right' caption='[[6hrl]], [[Resolution|resolution]] 2.60Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[6hrl]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6HRL OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6HRL FirstGlance]. <br> | |||
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr> | |||
[[Category: | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6hrl FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6hrl OCA], [http://pdbe.org/6hrl PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6hrl RCSB], [http://www.ebi.ac.uk/pdbsum/6hrl PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6hrl ProSAT]</span></td></tr> | ||
</table> | |||
== Function == | |||
[[http://www.uniprot.org/uniprot/KLH17_HUMAN KLH17_HUMAN]] Substrate-recognition component of some cullin-RING-based BCR (BTB-CUL3-RBX1) E3 ubiquitin-protein ligase complex. The BCR(KLHL17) mediates the ubiquitination and subsequenct degradation of GLUR6. May play a role in the actin-based neuronal function (By similarity). | |||
__TOC__ | |||
</StructureSection> | |||
[[Category: Arrowsmith, F]] | |||
[[Category: Bountra, C]] | |||
[[Category: Bullock, A N]] | |||
[[Category: Burgess-Brown, N]] | [[Category: Burgess-Brown, N]] | ||
[[Category: Chen, Z]] | |||
[[Category: Delft, F von]] | |||
[[Category: Edwards, C H]] | |||
[[Category: Newman, J A]] | |||
[[Category: Shrestha, L]] | [[Category: Shrestha, L]] | ||
[[Category: | [[Category: Sorrell, F J]] | ||
[[Category: Williams, E]] | [[Category: Williams, E]] | ||
[[Category: | [[Category: Actinfilin]] | ||
[[Category: | [[Category: Cullin 3 e3 ligase substrate adaptor]] | ||
[[Category: | [[Category: Homo sapien]] | ||
[[Category: | [[Category: Kelch domain]] | ||
[[Category: | [[Category: Ligase]] | ||
[[Category: | [[Category: Ubiquitination]] | ||