6hrl: Difference between revisions

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'''Unreleased structure'''


The entry 6hrl is ON HOLD
==Crystal structure of the Kelch domain of human KLHL17==
 
<StructureSection load='6hrl' size='340' side='right' caption='[[6hrl]], [[Resolution|resolution]] 2.60&Aring;' scene=''>
Authors: Chen, Z., Williams, E., Sorrell, F.J., Newman, J.A., Shrestha, L., Burgess-Brown, N., von Delft, F., Arrowsmith, F., Edwards, C.H., Bountra, C., Bullock, A.N.
== Structural highlights ==
 
<table><tr><td colspan='2'>[[6hrl]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6HRL OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6HRL FirstGlance]. <br>
Description: Crystal structure of the Kelch domain of human KLHL17
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
[[Category: Unreleased Structures]]
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6hrl FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6hrl OCA], [http://pdbe.org/6hrl PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6hrl RCSB], [http://www.ebi.ac.uk/pdbsum/6hrl PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6hrl ProSAT]</span></td></tr>
</table>
== Function ==
[[http://www.uniprot.org/uniprot/KLH17_HUMAN KLH17_HUMAN]] Substrate-recognition component of some cullin-RING-based BCR (BTB-CUL3-RBX1) E3 ubiquitin-protein ligase complex. The BCR(KLHL17) mediates the ubiquitination and subsequenct degradation of GLUR6. May play a role in the actin-based neuronal function (By similarity).
__TOC__
</StructureSection>
[[Category: Arrowsmith, F]]
[[Category: Bountra, C]]
[[Category: Bullock, A N]]
[[Category: Burgess-Brown, N]]
[[Category: Burgess-Brown, N]]
[[Category: Chen, Z]]
[[Category: Delft, F von]]
[[Category: Edwards, C H]]
[[Category: Newman, J A]]
[[Category: Shrestha, L]]
[[Category: Shrestha, L]]
[[Category: Newman, J.A]]
[[Category: Sorrell, F J]]
[[Category: Chen, Z]]
[[Category: Williams, E]]
[[Category: Williams, E]]
[[Category: Edwards, C.H]]
[[Category: Actinfilin]]
[[Category: Arrowsmith, F]]
[[Category: Cullin 3 e3 ligase substrate adaptor]]
[[Category: Von Delft, F]]
[[Category: Homo sapien]]
[[Category: Bountra, C]]
[[Category: Kelch domain]]
[[Category: Bullock, A.N]]
[[Category: Ligase]]
[[Category: Sorrell, F.J]]
[[Category: Ubiquitination]]