6ih0: Difference between revisions

Line 1:

~~'''Unreleased structure'''~~

~~The entry~~ 6ih0 ~~is ON HOLD~~

==Aquifex aeolicus LpxC complex with ACHN-975==

~~Authors~~: ~~Li, D~~.Y., ~~Fan~~, S., ~~Jin~~, Y.Y., ~~Zhang, C~~.~~, Lv, G~~.X.~~, Wu, G~~.T.~~, Yang, Z~~.Y.

== Structural highlights ==

<table><tr><td colspan='2'>[[6ih0]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6IH0 OCA]. For a guided tour on the structure components use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6IH0 FirstGlance].

~~Description~~: ~~Aquifex aeolicus LpxC complex with ACHN~~-~~975~~

</td></tr><tr id='ligand'><td class="sblockLbl">[[Ligand|Ligands:]]</td><td class="sblockDat"><scene name='pdbligand=A5F:N-[(2S)-3-azanyl-3-methyl-1-(oxidanylamino)-1-oxidanylidene-butan-2-yl]-4-[4-[(1R,2R)-2-(hydroxymethyl)cyclopropyl]buta-1,3-diynyl]benzamide'>A5F</scene>, <scene name='pdbligand=A5U:methyl+(2S)-2-azanyl-3-methyl-3-[(2-methylpropan-2-yl)oxycarbonylamino]butanoate'>A5U</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>

[[~~Category~~: ~~Unreleased Structures~~]]

<tr id='activity'><td class="sblockLbl">Activity:</td><td class="sblockDat">[http://en.wikipedia.org/wiki/UDP-3-O-acyl-N-acetylglucosamine_deacetylase UDP-3-O-acyl-N-acetylglucosamine deacetylase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.5.1.108 3.5.1.108] </td></tr>

[[~~Category~~: ~~Jin, Y~~.Y]]

<tr id='resources'><td class="sblockLbl">Resources:</td><td class="sblockDat">[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6ih0 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6ih0 OCA], [http://pdbe.org/6ih0 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6ih0 RCSB], [http://www.ebi.ac.uk/pdbsum/6ih0 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6ih0 ProSAT]</td></tr>

[[~~Category~~: ~~Yang, Z~~.Y]]

</table>

[[Category: ~~Li, D.Y~~]]

== Function ==

[[http://www.uniprot.org/uniprot/LPXC_AQUAE LPXC_AQUAE]] Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity).

__TOC__

</StructureSection>

[[Category: UDP-3-O-acyl-N-acetylglucosamine deacetylase]]

[[Category: Fan, S]]

[[Category: Jin, Y Y]]

[[Category: Li, D Y]]

[[Category: Lv, G X]]

[[Category: Wu, G T]]

[[Category: Yang, Z Y]]

[[Category: Zhang, C]]

[[Category: ~~Lv, G.X~~]]

[[Category: Antibiotic]]

[[Category: ~~Wu, G.T~~]]

[[Category: Complex]]

[[Category: Hydrolase-hydrolase inhibitor complex]]

[[Category: Inhibitor]]

Navigation menu

Page actions

Page actions

Personal tools

Navigation

Search

Tools

@@ Line 1: / Line 1: @@
-'''Unreleased structure'''
-The entry 6ih0 is ON HOLD
+==Aquifex aeolicus LpxC complex with ACHN-975==
+<StructureSection load='6ih0' size='340' side='right' caption='[[6ih0]], [[Resolution|resolution]] 1.21&Aring;' scene=''>
-Authors: Li, D.Y., Fan, S., Jin, Y.Y., Zhang, C., Lv, G.X., Wu, G.T., Yang, Z.Y.
+== Structural highlights ==
+<table><tr><td colspan='2'>[[6ih0]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6IH0 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6IH0 FirstGlance]. <br>
-Description: Aquifex aeolicus LpxC complex with ACHN-975
+</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=A5F:N-[(2S)-3-azanyl-3-methyl-1-(oxidanylamino)-1-oxidanylidene-butan-2-yl]-4-[4-[(1R,2R)-2-(hydroxymethyl)cyclopropyl]buta-1,3-diynyl]benzamide'>A5F</scene>, <scene name='pdbligand=A5U:methyl+(2S)-2-azanyl-3-methyl-3-[(2-methylpropan-2-yl)oxycarbonylamino]butanoate'>A5U</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
-[[Category: Unreleased Structures]]
+<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/UDP-3-O-acyl-N-acetylglucosamine_deacetylase UDP-3-O-acyl-N-acetylglucosamine deacetylase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.5.1.108 3.5.1.108] </span></td></tr>
-[[Category: Jin, Y.Y]]
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6ih0 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6ih0 OCA], [http://pdbe.org/6ih0 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6ih0 RCSB], [http://www.ebi.ac.uk/pdbsum/6ih0 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6ih0 ProSAT]</span></td></tr>
-[[Category: Yang, Z.Y]]
+</table>
-[[Category: Li, D.Y]]
+== Function ==
+[[http://www.uniprot.org/uniprot/LPXC_AQUAE LPXC_AQUAE]] Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity).
+__TOC__
+</StructureSection>
+[[Category: UDP-3-O-acyl-N-acetylglucosamine deacetylase]]
 [[Category: Fan, S]]
+[[Category: Jin, Y Y]]
+[[Category: Li, D Y]]
+[[Category: Lv, G X]]
+[[Category: Wu, G T]]
+[[Category: Yang, Z Y]]
 [[Category: Zhang, C]]
-[[Category: Lv, G.X]]
+[[Category: Antibiotic]]
-[[Category: Wu, G.T]]
+[[Category: Complex]]
+[[Category: Hydrolase-hydrolase inhibitor complex]]
+[[Category: Inhibitor]]