6a96: Difference between revisions
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==Cryo-EM structure of the human alpha5beta3 GABAA receptor in complex with GABA and Nb25== | ==Cryo-EM structure of the human alpha5beta3 GABAA receptor in complex with GABA and Nb25== | ||
< | <SX load='6a96' size='340' side='right' viewer='molstar' caption='[[6a96]], [[Resolution|resolution]] 3.51Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[6a96]] is a 8 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6A96 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6A96 FirstGlance]. <br> | <table><tr><td colspan='2'>[[6a96]] is a 8 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6A96 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6A96 FirstGlance]. <br> | ||
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== Function == | == Function == | ||
[[http://www.uniprot.org/uniprot/GBRA5_HUMAN GBRA5_HUMAN]] GABA, the major inhibitory neurotransmitter in the vertebrate brain, mediates neuronal inhibition by binding to the GABA/benzodiazepine receptor and opening an integral chloride channel. [[http://www.uniprot.org/uniprot/GBRB3_HUMAN GBRB3_HUMAN]] GABA, the major inhibitory neurotransmitter in the vertebrate brain, mediates neuronal inhibition by binding to the GABA/benzodiazepine receptor and opening an integral chloride channel. | [[http://www.uniprot.org/uniprot/GBRA5_HUMAN GBRA5_HUMAN]] GABA, the major inhibitory neurotransmitter in the vertebrate brain, mediates neuronal inhibition by binding to the GABA/benzodiazepine receptor and opening an integral chloride channel. [[http://www.uniprot.org/uniprot/GBRB3_HUMAN GBRB3_HUMAN]] GABA, the major inhibitory neurotransmitter in the vertebrate brain, mediates neuronal inhibition by binding to the GABA/benzodiazepine receptor and opening an integral chloride channel. | ||
==See Also== | |||
*[[GABA receptor 3D structures|GABA receptor 3D structures]] | |||
__TOC__ | __TOC__ | ||
</ | </SX> | ||
[[Category: Large Structures]] | |||
[[Category: Bi, G Q]] | [[Category: Bi, G Q]] | ||
[[Category: Cui, Y]] | [[Category: Cui, Y]] | ||
Revision as of 20:21, 6 March 2020
Cryo-EM structure of the human alpha5beta3 GABAA receptor in complex with GABA and Nb25
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