User:Wally Novak/Sandbox Whitaker: Difference between revisions
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Wally Novak (talk | contribs) New page: ==U5 snRNP== <StructureSection load='1stp' size='340' side='right' caption='Caption for this structure' scene=''> This is a default text for your page '''Wally Novak/Sandbox Whitaker'''. C... |
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Internal loop 1: The level of conservation is highest in the 3' half of ILl, where the sequence is invariably CCG in the fungi. In contrast, the fungal and nonfungal sequences that define the 5' halves of ILl are only moderately conserved in comparison to Li and the 3' halves of ILl. Nevertheless, the 5' halves of ILl in all species of U5 include an invariant CG dinucleotide at positions 79 and 80. | Internal loop 1: The level of conservation is highest in the 3' half of ILl, where the sequence is invariably CCG in the fungi. In contrast, the fungal and nonfungal sequences that define the 5' halves of ILl are only moderately conserved in comparison to Li and the 3' halves of ILl. Nevertheless, the 5' halves of ILl in all species of U5 include an invariant CG dinucleotide at positions 79 and 80. | ||
Sm protein binding site: Putative Sm protein binding sites could be identified in all U5 sequences, thus highlighting the importance of this sequence motif in snRNP assembly (14, 21). The consensus sequence of the fungal U5 Sm sites is R(U)5NGgaa. | Sm protein binding site: Putative Sm protein binding sites could be identified in all U5 sequences, thus highlighting the importance of this sequence motif in snRNP assembly (14, 21). The consensus sequence of the fungal U5 Sm sites is R(U)5NGgaa. | ||
== Protein | == Protein Interactions == | ||
The U5 snRNA combines with three other structures to form the U5 snRNP which combines with U4 and U6 to form tri-complex which then becomes incorporated into the spliceosome. | The U5 snRNA combines with three other structures to form the U5 snRNP which combines with U4 and U6 to form tri-complex which then becomes incorporated into the spliceosome. | ||
== 3D Structures == | == 3D Structures == | ||
