5zsy: Difference between revisions

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'''Unreleased structure'''


The entry 5zsy is ON HOLD  until Paper Publication
==RBM10-RRM2 domain and its lung cancer related mutant==
 
<StructureSection load='5zsy' size='340' side='right'caption='[[5zsy]], [[NMR_Ensembles_of_Models | 20 NMR models]]' scene=''>
Authors: Qin, H.
== Structural highlights ==
 
<table><tr><td colspan='2'>[[5zsy]] is a 1 chain structure. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5ZSY OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5ZSY FirstGlance]. <br>
Description: RBM10-RRM2 domain and its lung cancer related mutant
</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5zsy FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5zsy OCA], [http://pdbe.org/5zsy PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5zsy RCSB], [http://www.ebi.ac.uk/pdbsum/5zsy PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5zsy ProSAT]</span></td></tr>
[[Category: Unreleased Structures]]
</table>
== Disease ==
[[http://www.uniprot.org/uniprot/RBM10_HUMAN RBM10_HUMAN]] TARP syndrome. TARP syndrome (TARPS) [MIM:[http://omim.org/entry/311900 311900]]: A disorder characterized by the Robin sequence (micrognathia, glossoptosis and cleft palate), talipes equinovarus and cardiac defects. Note=The disease is caused by mutations affecting the gene represented in this entry.<ref>PMID:20451169</ref> 
== Function ==
[[http://www.uniprot.org/uniprot/RBM10_HUMAN RBM10_HUMAN]] May be involved in post-transcriptional processing, most probably in mRNA splicing. Binds to RNA homopolymers, with a preference for poly(G) and poly(U) and little for poly(A) (By similarity).<ref>PMID:18315527</ref> 
== References ==
<references/>
__TOC__
</StructureSection>
[[Category: Large Structures]]
[[Category: Qin, H]]
[[Category: Qin, H]]
[[Category: Classical folding and binding mode]]
[[Category: Rna binding protein]]