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| [[Image:2r2l.jpg|left|200px]] | | [[Image:2r2l.jpg|left|200px]] |
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| {{Structure
| | <!-- |
| |PDB= 2r2l |SIZE=350|CAPTION= <scene name='initialview01'>2r2l</scene>, resolution 2.230Å
| | The line below this paragraph, containing "STRUCTURE_2r2l", creates the "Structure Box" on the page. |
| |SITE= <scene name='pdbsite=AC1:Zn+Binding+Site+For+Residue+B+1'>AC1</scene>, <scene name='pdbsite=AC2:Fpp+Binding+Site+For+Residue+B+424'>AC2</scene> and <scene name='pdbsite=AC3:Pb9+Binding+Site+For+Residue+B+425'>AC3</scene>
| | You may change the PDB parameter (which sets the PDB file loaded into the applet) |
| |LIGAND= <scene name='pdbligand=FPP:FARNESYL+DIPHOSPHATE'>FPP</scene>, <scene name='pdbligand=PB9:METHYL+4-{[{(3S)-6-CYANO-1-[(1-METHYL-1H-IMIDAZOL-5-YL)METHYL]-1,2,3,4-TETRAHYDROQUINOLIN-3-YL}(PYRIDIN-2-YLSULFONYL)AMINO]METHYL}PIPERIDINE-1-CARBOXYLATE'>PB9</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene>
| | or the SCENE parameter (which sets the initial scene displayed when the page is loaded), |
| |ACTIVITY= <span class='plainlinks'>[http://en.wikipedia.org/wiki/Protein_farnesyltransferase Protein farnesyltransferase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.5.1.58 2.5.1.58] </span>
| | or leave the SCENE parameter empty for the default display. |
| |GENE= Fnta ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=10116 Rattus norvegicus]), Fntb ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=10116 Rattus norvegicus]) | | --> |
| |DOMAIN= | | {{STRUCTURE_2r2l| PDB=2r2l | SCENE= }} |
| |RELATEDENTRY=
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| |RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2r2l FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2r2l OCA], [http://www.ebi.ac.uk/pdbsum/2r2l PDBsum], [http://www.rcsb.org/pdb/explore.do?structureId=2r2l RCSB]</span>
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| }} | |
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| '''Structure of Farnesyl Protein Transferase bound to PB-93''' | | '''Structure of Farnesyl Protein Transferase bound to PB-93''' |
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| [[Category: Strickland, C O.]] | | [[Category: Strickland, C O.]] |
| [[Category: Voorhis, W.]] | | [[Category: Voorhis, W.]] |
| [[Category: fpt]] | | [[Category: Fpt]] |
| [[Category: malaria]] | | [[Category: Malaria]] |
| [[Category: metal-binding]] | | [[Category: Metal-binding]] |
| [[Category: phosphorylation]] | | [[Category: Phosphorylation]] |
| [[Category: prenyltransferase]] | | [[Category: Prenyltransferase]] |
| [[Category: transferase]] | | [[Category: Transferase]] |
| [[Category: zinc]] | | [[Category: Zinc]] |
| | | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sun May 4 16:07:56 2008'' |
| ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Mar 31 04:55:52 2008'' | |
