2ran: Difference between revisions

From Proteopedia
Jump to navigationJump to search
← Older editNewer edit →
OCA (talk | contribs)
Bots, Bureaucrats, journal, Administrators
3,328,572 edits
No edit summary
OCA (talk | contribs)
Bots, Bureaucrats, journal, Administrators
3,328,572 edits
No edit summary
Line 1: Line 1:
[[Image:2ran.jpg|left|200px]]
[[Image:2ran.jpg|left|200px]]


{{Structure
<!--
|PDB= 2ran |SIZE=350|CAPTION= <scene name='initialview01'>2ran</scene>, resolution 1.89&Aring;
The line below this paragraph, containing "STRUCTURE_2ran", creates the "Structure Box" on the page.
|SITE=
You may change the PDB parameter (which sets the PDB file loaded into the applet)
|LIGAND= <scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
|ACTIVITY=
or leave the SCENE parameter empty for the default display.
|GENE=
-->
|DOMAIN=
{{STRUCTURE_2ran| PDB=2ran  | SCENE= }}  
|RELATEDENTRY=
|RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2ran FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2ran OCA], [http://www.ebi.ac.uk/pdbsum/2ran PDBsum], [http://www.rcsb.org/pdb/explore.do?structureId=2ran RCSB]</span>
}}


'''RAT ANNEXIN V CRYSTAL STRUCTURE: CA2+-INDUCED CONFORMATIONAL CHANGES'''
'''RAT ANNEXIN V CRYSTAL STRUCTURE: CA2+-INDUCED CONFORMATIONAL CHANGES'''
Line 30: Line 27:
[[Category: Kaetzel, M A.]]
[[Category: Kaetzel, M A.]]
[[Category: Seaton, B A.]]
[[Category: Seaton, B A.]]
[[Category: calcium/phospholipid-binding protein]]
[[Category: Calcium/phospholipid-binding protein]]
 
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sun May  4 16:33:31 2008''
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Mar 31 04:58:20 2008''

Revision as of 13:33, 4 May 2008

File:2ran.jpg

Template:STRUCTURE 2ran

RAT ANNEXIN V CRYSTAL STRUCTURE: CA2+-INDUCED CONFORMATIONAL CHANGES


Overview

Annexins are a family of calcium- and phospholipid-binding proteins implicated in mediating membrane-related processes such as secretion, signal transduction, and ion channel activity. The crystal structure of rat annexin V was solved to 1.9 angstrom resolution by multiple isomorphous replacement. Unlike previously solved annexin V structures, all four domains bound calcium in this structure. Calcium binding in the third domain induced a large relocation of the calcium-binding loop regions, exposing the single tryptophan residue to the solvent. These alterations in annexin V suggest a role for domain 3 in calcium-triggered interaction with phospholipid membranes.

About this Structure

2RAN is a Single protein structure of sequence from Rattus norvegicus. Full crystallographic information is available from OCA.

Reference

Rat annexin V crystal structure: Ca(2+)-induced conformational changes., Concha NO, Head JF, Kaetzel MA, Dedman JR, Seaton BA, Science. 1993 Sep 3;261(5126):1321-4. PMID:8362244 Page seeded by OCA on Sun May 4 16:33:31 2008

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "https://proteopedia.org/index.php?title=2ran&oldid=520867"