5you: Difference between revisions

Line 1:

~~'''Unreleased structure'''~~

~~The entry~~ 5you ~~is ON HOLD until Nov 08 2019~~

==Crystal structure of BRD4-BD1 bound with hjp64==

~~Authors~~: ~~Bing, X~~., ~~Jianping~~, H., ~~Yanlian~~, L., ~~Danyan~~, C.

== Structural highlights ==

<table><tr><td colspan='2'>[[5you]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5YOU OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5YOU FirstGlance]. <br>

~~Description~~: ~~Crystal structure~~ of BRD4-~~BD1 bound with hjp64~~

</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=8XX:(3~{R})-4-cyclopropyl-~{N},1,3-trimethyl-~{N}-(4-methylphenyl)-2-oxidanylidene-3~{H}-quinoxaline-6-carboxamide'>8XX</scene></td></tr>

[[Category: ~~Unreleased Structures~~]]

<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5you FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5you OCA], [http://pdbe.org/5you PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5you RCSB], [http://www.ebi.ac.uk/pdbsum/5you PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5you ProSAT]</span></td></tr>

</table>

== Disease ==

[[http://www.uniprot.org/uniprot/BRD4_HUMAN BRD4_HUMAN]] Note=A chromosomal aberration involving BRD4 is found in a rare, aggressive, and lethal carcinoma arising in midline organs of young people. Translocation t(15;19)(q14;p13) with NUT which produces a BRD4-NUT fusion protein.<ref>PMID:12543779</ref> <ref>PMID:11733348</ref>

== Function ==

[[http://www.uniprot.org/uniprot/BRD4_HUMAN BRD4_HUMAN]] Plays a role in a process governing chromosomal dynamics during mitosis (By similarity).

== References ==

__TOC__

</StructureSection>

[[Category: Bing, X]]

[[Category: Danyan, C]]

[[Category: Jianping, H]]

[[Category: Yanlian, L]]

[[Category: ~~Danyan, C~~]]

[[Category: Bromodomain]]

[[Category: ~~Bing, X~~]]

[[Category: Transcription-inhibitor complex]]

Navigation menu

Page actions

Page actions

Personal tools

Navigation

Search

Tools

@@ Line 1: / Line 1: @@
-'''Unreleased structure'''
-The entry 5you is ON HOLD  until Nov 08 2019
+==Crystal structure of BRD4-BD1 bound with hjp64==
+<StructureSection load='5you' size='340' side='right' caption='[[5you]], [[Resolution|resolution]] 1.50&Aring;' scene=''>
-Authors: Bing, X., Jianping, H., Yanlian, L., Danyan, C.
+== Structural highlights ==
+<table><tr><td colspan='2'>[[5you]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5YOU OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5YOU FirstGlance]. <br>
-Description: Crystal structure of BRD4-BD1 bound with hjp64
+</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=8XX:(3~{R})-4-cyclopropyl-~{N},1,3-trimethyl-~{N}-(4-methylphenyl)-2-oxidanylidene-3~{H}-quinoxaline-6-carboxamide'>8XX</scene></td></tr>
-[[Category: Unreleased Structures]]
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5you FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5you OCA], [http://pdbe.org/5you PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5you RCSB], [http://www.ebi.ac.uk/pdbsum/5you PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5you ProSAT]</span></td></tr>
+</table>
+== Disease ==
+[[http://www.uniprot.org/uniprot/BRD4_HUMAN BRD4_HUMAN]] Note=A chromosomal aberration involving BRD4 is found in a rare, aggressive, and lethal carcinoma arising in midline organs of young people. Translocation t(15;19)(q14;p13) with NUT which produces a BRD4-NUT fusion protein.<ref>PMID:12543779</ref> <ref>PMID:11733348</ref>
+== Function ==
+[[http://www.uniprot.org/uniprot/BRD4_HUMAN BRD4_HUMAN]] Plays a role in a process governing chromosomal dynamics during mitosis (By similarity).
+== References ==
+<references/>
+__TOC__
+</StructureSection>
+[[Category: Bing, X]]
+[[Category: Danyan, C]]
 [[Category: Jianping, H]]
 [[Category: Yanlian, L]]
-[[Category: Danyan, C]]
+[[Category: Bromodomain]]
-[[Category: Bing, X]]
+[[Category: Transcription-inhibitor complex]]