6hya: Difference between revisions

Line 1:

~~'''Unreleased structure'''~~

~~The entry~~ 6hya is ~~ON HOLD~~

==THE GLIC PENTAMERIC LIGAND-GATED ION CHANNEL MUTANT Q193L==

~~Authors~~: Hu, H.D., ~~Delarue~~, M.

== Structural highlights ==

<table><tr><td colspan='2'>[[6hya]] is a 5 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6HYA OCA]. For a guided tour on the structure components use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6HYA FirstGlance].

~~Description: THE GLIC PENTAMERIC LIGAND-GATED ION CHANNEL MUTANT Q193L~~

</td></tr><tr id='ligand'><td class="sblockLbl">[[Ligand|Ligands:]]</td><td class="sblockDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=LMT:DODECYL-BETA-D-MALTOSIDE'>LMT</scene></td></tr>

[[~~Category~~: ~~Unreleased Structures~~]]

<tr id='related'><td class="sblockLbl">[[Related_structure|Related:]]</td><td class="sblockDat">[[6hy9|6hy9]]</td></tr>

<tr id='resources'><td class="sblockLbl">Resources:</td><td class="sblockDat">[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6hya FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6hya OCA], [http://pdbe.org/6hya PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6hya RCSB], [http://www.ebi.ac.uk/pdbsum/6hya PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6hya ProSAT]</td></tr>

</table>

== Function ==

[[http://www.uniprot.org/uniprot/GLIC_GLOVI GLIC_GLOVI]] Cationic channel with similar permeabilities for Na(+) and K(+), that is activated by an increase of the proton concentration on the extracellular side. Displays no permeability for chloride ions. Shows slow kinetics of activation, no desensitization and a single channel conductance of 8 pS. Might contribute to adaptation to external pH change.<ref>PMID:17167423</ref>

== References ==

__TOC__

</StructureSection>

[[Category: Delarue, M]]

[[Category: Hu, H.D]]

[[Category: Hu, H D]]

[[Category: Ion channel]]

[[Category: Membrane protein]]

[[Category: Pentameric transmembrane channel]]

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@@ Line 1: / Line 1: @@
-'''Unreleased structure'''
-The entry 6hya is ON HOLD
+==THE GLIC PENTAMERIC LIGAND-GATED ION CHANNEL MUTANT Q193L==
+<StructureSection load='6hya' size='340' side='right' caption='[[6hya]], [[Resolution|resolution]] 3.39&Aring;' scene=''>
-Authors: Hu, H.D., Delarue, M.
+== Structural highlights ==
+<table><tr><td colspan='2'>[[6hya]] is a 5 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6HYA OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6HYA FirstGlance]. <br>
-Description: THE GLIC PENTAMERIC LIGAND-GATED ION CHANNEL MUTANT Q193L
+</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=LMT:DODECYL-BETA-D-MALTOSIDE'>LMT</scene></td></tr>
-[[Category: Unreleased Structures]]
+<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[6hy9|6hy9]]</td></tr>
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6hya FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6hya OCA], [http://pdbe.org/6hya PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6hya RCSB], [http://www.ebi.ac.uk/pdbsum/6hya PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6hya ProSAT]</span></td></tr>
+</table>
+== Function ==
+[[http://www.uniprot.org/uniprot/GLIC_GLOVI GLIC_GLOVI]] Cationic channel with similar permeabilities for Na(+) and K(+), that is activated by an increase of the proton concentration on the extracellular side. Displays no permeability for chloride ions. Shows slow kinetics of activation, no desensitization and a single channel conductance of 8 pS. Might contribute to adaptation to external pH change.<ref>PMID:17167423</ref>
+== References ==
+<references/>
+__TOC__
+</StructureSection>
 [[Category: Delarue, M]]
-[[Category: Hu, H.D]]
+[[Category: Hu, H D]]
+[[Category: Ion channel]]
+[[Category: Membrane protein]]
+[[Category: Pentameric transmembrane channel]]