6ijx: Difference between revisions

Line 1:

~~'''Unreleased structure'''~~

~~The entry~~ 6ijx is ~~ON HOLD until Paper Publication~~

==Crystal Structure of AKR1C1 complexed with meclofenamic acid==

~~Authors~~: ~~Zheng~~, X., ~~Zhao~~, Y., ~~Zhang~~, L.~~, Zhang, H~~., ~~Chen, Y~~.~~, Hu, X~~.

== Structural highlights ==

<table><tr><td colspan='2'>[[6ijx]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6IJX OCA]. For a guided tour on the structure components use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6IJX FirstGlance].

~~Description~~: ~~Crystal Structure~~ of ~~AKR1C1 complexed with meclofenamic~~ acid

</td></tr><tr id='ligand'><td class="sblockLbl">[[Ligand|Ligands:]]</td><td class="sblockDat"><scene name='pdbligand=JMS:2-[(2,6-DICHLORO-3-METHYL-PHENYL)AMINO]BENZOIC+ACID'>JMS</scene>, <scene name='pdbligand=NAP:NADP+NICOTINAMIDE-ADENINE-DINUCLEOTIDE+PHOSPHATE'>NAP</scene></td></tr>

[[Category: ~~Unreleased~~ Structures]]

<tr id='related'><td class="sblockLbl">[[Related_structure|Related:]]</td><td class="sblockDat">[[6a7a|6a7a]], [[6a7b|6a7b]]</td></tr>

<tr id='resources'><td class="sblockLbl">Resources:</td><td class="sblockDat">[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6ijx FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6ijx OCA], [http://pdbe.org/6ijx PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6ijx RCSB], [http://www.ebi.ac.uk/pdbsum/6ijx PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6ijx ProSAT]</td></tr>

</table>

== Function ==

[[http://www.uniprot.org/uniprot/AK1C1_HUMAN AK1C1_HUMAN]] Converts progesterone to its inactive form, 20-alpha-dihydroxyprogesterone (20-alpha-OHP). In the liver and intestine, may have a role in the transport of bile. May have a role in monitoring the intrahepatic bile acid concentration. Has a low bile-binding ability. May play a role in myelin formation.<ref>PMID:11013348</ref> <ref>PMID:8573067</ref>

== References ==

__TOC__

</StructureSection>

[[Category: Large Structures]]

[[Category: Chen, Y]]

[[Category: Hu, X]]

[[Category: Zhang, H]]

[[Category: Zhang, L]]

[[Category: Zhao, Y]]

~~[[Category: Chen, Y]]~~

[[Category: Zheng, X]]

[[Category: ~~Hu, X~~]]

[[Category: Complex]]

[[Category: Inhibitor]]

[[Category: Oxidoreductase]]

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@@ Line 1: / Line 1: @@
-'''Unreleased structure'''
-The entry 6ijx is ON HOLD  until Paper Publication
+==Crystal Structure of AKR1C1 complexed with meclofenamic acid==
+<StructureSection load='6ijx' size='340' side='right'caption='[[6ijx]], [[Resolution|resolution]] 2.20&Aring;' scene=''>
-Authors: Zheng, X., Zhao, Y., Zhang, L., Zhang, H., Chen, Y., Hu, X.
+== Structural highlights ==
+<table><tr><td colspan='2'>[[6ijx]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6IJX OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6IJX FirstGlance]. <br>
-Description: Crystal Structure of AKR1C1 complexed with meclofenamic acid
+</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=JMS:2-[(2,6-DICHLORO-3-METHYL-PHENYL)AMINO]BENZOIC+ACID'>JMS</scene>, <scene name='pdbligand=NAP:NADP+NICOTINAMIDE-ADENINE-DINUCLEOTIDE+PHOSPHATE'>NAP</scene></td></tr>
-[[Category: Unreleased Structures]]
+<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[6a7a|6a7a]], [[6a7b|6a7b]]</td></tr>
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6ijx FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6ijx OCA], [http://pdbe.org/6ijx PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6ijx RCSB], [http://www.ebi.ac.uk/pdbsum/6ijx PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6ijx ProSAT]</span></td></tr>
+</table>
+== Function ==
+[[http://www.uniprot.org/uniprot/AK1C1_HUMAN AK1C1_HUMAN]] Converts progesterone to its inactive form, 20-alpha-dihydroxyprogesterone (20-alpha-OHP). In the liver and intestine, may have a role in the transport of bile. May have a role in monitoring the intrahepatic bile acid concentration. Has a low bile-binding ability. May play a role in myelin formation.<ref>PMID:11013348</ref> <ref>PMID:8573067</ref>
+== References ==
+<references/>
+__TOC__
+</StructureSection>
+[[Category: Large Structures]]
+[[Category: Chen, Y]]
+[[Category: Hu, X]]
 [[Category: Zhang, H]]
 [[Category: Zhang, L]]
 [[Category: Zhao, Y]]
-[[Category: Chen, Y]]
 [[Category: Zheng, X]]
-[[Category: Hu, X]]
+[[Category: Complex]]
+[[Category: Inhibitor]]
+[[Category: Oxidoreductase]]