6ioz: Difference between revisions

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'''Unreleased structure'''


The entry 6ioz is ON HOLD
==Structural insights of idursulfase beta==
 
<StructureSection load='6ioz' size='340' side='right' caption='[[6ioz]], [[Resolution|resolution]] 3.10&Aring;' scene=''>
Authors: Kim, H., Kim, D., Hong, J., Lee, K., Seo, J., Oh, B.H.
== Structural highlights ==
 
<table><tr><td colspan='2'>[[6ioz]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6IOZ OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6IOZ FirstGlance]. <br>
Description: Structural insights of idursulfase beta
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=FUC:ALPHA-L-FUCOSE'>FUC</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene></td></tr>
[[Category: Unreleased Structures]]
<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=ALS:(3S)-3-(SULFOOXY)-L-SERINE'>ALS</scene></td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">IDS, SIDS ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Iduronate-2-sulfatase Iduronate-2-sulfatase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.1.6.13 3.1.6.13] </span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6ioz FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6ioz OCA], [http://pdbe.org/6ioz PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6ioz RCSB], [http://www.ebi.ac.uk/pdbsum/6ioz PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6ioz ProSAT]</span></td></tr>
</table>
== Disease ==
[[http://www.uniprot.org/uniprot/IDS_HUMAN IDS_HUMAN]] Mucopolysaccharidosis type 2, attenuated form;Mucopolysaccharidosis type 2, severe form. The disease is caused by mutations affecting the gene represented in this entry.  
== Function ==
[[http://www.uniprot.org/uniprot/IDS_HUMAN IDS_HUMAN]] Required for the lysosomal degradation of heparan sulfate and dermatan sulfate.
__TOC__
</StructureSection>
[[Category: Human]]
[[Category: Iduronate-2-sulfatase]]
[[Category: Hong, J]]
[[Category: Kim, D]]
[[Category: Kim, H]]
[[Category: Kim, H]]
[[Category: Hong, J]]
[[Category: Lee, K]]
[[Category: Lee, K]]
[[Category: Oh, B H]]
[[Category: Seo, J]]
[[Category: Seo, J]]
[[Category: Oh, B.H]]
[[Category: Alpha-l-iduronate sulfate sulfatase]]
[[Category: Kim, D]]
[[Category: Hydrolase]]
[[Category: Iduronate 2-sulfatase 14kda chain]]
[[Category: Iduronate 2-sulfatase 42kda chain]]
[[Category: Idursulfase beta]]
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