6i3r: Difference between revisions
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==Structure, dynamics and roX2-lncRNA binding of tandem double-stranded RNA binding domains dsRBD1/2 of Drosophila helicase MLE== | |||
<StructureSection load='6i3r' size='340' side='right' caption='[[6i3r]], [[NMR_Ensembles_of_Models | 10 NMR models]]' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[6i3r]] is a 1 chain structure. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6I3R OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6I3R FirstGlance]. <br> | |||
</td></tr><tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/RNA_helicase RNA helicase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.6.4.13 3.6.4.13] </span></td></tr> | |||
[[Category: | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6i3r FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6i3r OCA], [http://pdbe.org/6i3r PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6i3r RCSB], [http://www.ebi.ac.uk/pdbsum/6i3r PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6i3r ProSAT]</span></td></tr> | ||
</table> | |||
== Function == | |||
[[http://www.uniprot.org/uniprot/MLE_DROME MLE_DROME]] Required in males for dosage compensation of X chromosome linked genes. Mle, msl-1 and msl-3 are colocalized on X chromosome. Each of the msl proteins requires all the other msls for wild-type X-chromosome binding. Probably unwinds double-stranded DNA and RNA in a 3' to 5' direction.<ref>PMID:1653648</ref> | |||
== References == | |||
<references/> | |||
__TOC__ | |||
</StructureSection> | |||
[[Category: RNA helicase]] | |||
[[Category: Buelow, S v]] | |||
[[Category: Hennig, J]] | |||
[[Category: Jagtap, P K.A]] | |||
[[Category: Masiewicz, P]] | [[Category: Masiewicz, P]] | ||
[[Category: Simon, B]] | [[Category: Simon, B]] | ||
[[Category: | [[Category: Dsrbd]] | ||
[[Category: Helicase]] | |||
[[Category: Rna binding protein]] | |||
