6mss: Difference between revisions
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==Diversity in the type II Natural Killer T cell receptor repertoire and antigen specificity leads to differing CD1d docking strategies== | |||
<StructureSection load='6mss' size='340' side='right'caption='[[6mss]], [[Resolution|resolution]] 3.00Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[6mss]] is a 4 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6MSS OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6MSS FirstGlance]. <br> | |||
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene>, <scene name='pdbligand=SRV:(2S)-2-(heptadecanoyloxy)-3-{[(10S)-10-methyloctadecanoyl]oxy}propyl+alpha-D-glucopyranosiduronic+acid'>SRV</scene></td></tr> | |||
[[Category: | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6mss FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6mss OCA], [http://pdbe.org/6mss PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6mss RCSB], [http://www.ebi.ac.uk/pdbsum/6mss PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6mss ProSAT]</span></td></tr> | ||
</table> | |||
== Function == | |||
[[http://www.uniprot.org/uniprot/B2MG_MOUSE B2MG_MOUSE]] Component of the class I major histocompatibility complex (MHC). Involved in the presentation of peptide antigens to the immune system. [[http://www.uniprot.org/uniprot/CD1D1_MOUSE CD1D1_MOUSE]] Antigen-presenting protein that binds self and non-self glycolipids and presents them to T-cell receptors on natural killer T-cells.<ref>PMID:11754812</ref> <ref>PMID:16314439</ref> <ref>PMID:16007091</ref> | |||
== References == | |||
<references/> | |||
__TOC__ | |||
</StructureSection> | |||
[[Category: Large Structures]] | |||
[[Category: Nours, J Le]] | |||
[[Category: Praveena, T]] | |||
[[Category: Rossjohn, J]] | |||
[[Category: Sundararaj, S]] | |||
[[Category: Cd1d molecule]] | |||
[[Category: Immune system]] | |||
[[Category: Microbial lipid antigen]] | |||
[[Category: Nkt cell]] | |||
Revision as of 10:27, 2 October 2019
Diversity in the type II Natural Killer T cell receptor repertoire and antigen specificity leads to differing CD1d docking strategies
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