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==Crystal structure of L-rhamnonate dehydratase from Salmonella typhimurium==
==Crystal structure of L-rhamnonate dehydratase from Salmonella typhimurium==
<StructureSection load='2gsh' size='340' side='right' caption='[[2gsh]], [[Resolution|resolution]] 2.39&Aring;' scene=''>
<StructureSection load='2gsh' size='340' side='right'caption='[[2gsh]]' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[2gsh]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Salty Salty]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2GSH OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2GSH FirstGlance]. <br>
<table><tr><td colspan='2'>Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2GSH OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2GSH FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2gsh FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2gsh OCA], [https://pdbe.org/2gsh PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2gsh RCSB], [https://www.ebi.ac.uk/pdbsum/2gsh PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2gsh ProSAT], [https://www.topsan.org/Proteins/NYSGXRC/2gsh TOPSAN]</span></td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">STM2291 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=99287 SALTY])</td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/L-rhamnonate_dehydratase L-rhamnonate dehydratase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=4.2.1.90 4.2.1.90] </span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2gsh FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2gsh OCA], [http://pdbe.org/2gsh PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2gsh RCSB], [http://www.ebi.ac.uk/pdbsum/2gsh PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2gsh ProSAT], [http://www.topsan.org/Proteins/NYSGXRC/2gsh TOPSAN]</span></td></tr>
</table>
</table>
== Function ==
[[http://www.uniprot.org/uniprot/RHMD_SALTY RHMD_SALTY]] Catalyzes the dehydration of L-rhamnonate to 2-keto-3-deoxy-L-rhamnonate (KDR). Can also dehydrate L-lyxonate and L-mannonate, although less efficiently, but not 2-keto-4-hydroxyheptane-1,7-dioate.<ref>PMID:18754693</ref> 
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2gsh ConSurf].
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2gsh ConSurf].
<div style="clear:both"></div>
<div style="clear:both"></div>
== References ==
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: L-rhamnonate dehydratase]]
[[Category: Large Structures]]
[[Category: Salty]]
[[Category: Adams JM]]
[[Category: Adams, J M]]
[[Category: Almo SC]]
[[Category: Almo, S C]]
[[Category: Burley SK]]
[[Category: Burley, S K]]
[[Category: Dickey M]]
[[Category: Dickey, M]]
[[Category: Gerlt J]]
[[Category: Gerlt, J]]
[[Category: Malashkevich VN]]
[[Category: Malashkevich, V N]]
[[Category: Patskovsky Y]]
[[Category: Structural genomic]]
[[Category: Sauder JM]]
[[Category: Patskovsky, Y]]
[[Category: Wasserman SR]]
[[Category: Sauder, J M]]
[[Category: Wasserman, S R]]
[[Category: Enolase]]
[[Category: Lyase]]
[[Category: NYSGXRC, New York SGX Research Center for Structural Genomics]]
[[Category: PSI, Protein structure initiative]]
Retrieved from "https://proteopedia.org/2gsh"