2vku: Difference between revisions

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[[Image:2vku.jpg|left|200px]]
[[Image:2vku.jpg|left|200px]]


{{Structure
<!--
|PDB= 2vku |SIZE=350|CAPTION= <scene name='initialview01'>2vku</scene>, resolution 1.95&Aring;
The line below this paragraph, containing "STRUCTURE_2vku", creates the "Structure Box" on the page.
|SITE= <scene name='pdbsite=AC1:Dbe+Binding+Site+For+Residue+A+1446'>AC1</scene>, <scene name='pdbsite=AC2:Dbe+Binding+Site+For+Residue+A+1447'>AC2</scene>, <scene name='pdbsite=AC3:Dbe+Binding+Site+For+Residue+A+1448'>AC3</scene>, <scene name='pdbsite=AC4:Dbe+Binding+Site+For+Residue+A+1449'>AC4</scene>, <scene name='pdbsite=AC5:Hem+Binding+Site+For+Residue+A+1450'>AC5</scene>, <scene name='pdbsite=AC6:So4+Binding+Site+For+Residue+A+1452'>AC6</scene>, <scene name='pdbsite=AC7:So4+Binding+Site+For+Residue+A+1453'>AC7</scene>, <scene name='pdbsite=AC8:So4+Binding+Site+For+Residue+A+1454'>AC8</scene>, <scene name='pdbsite=AC9:So4+Binding+Site+For+Residue+A+1455'>AC9</scene>, <scene name='pdbsite=BC1:So4+Binding+Site+For+Residue+A+1456'>BC1</scene> and <scene name='pdbsite=BC2:So4+Binding+Site+For+Residue+A+1457'>BC2</scene>
You may change the PDB parameter (which sets the PDB file loaded into the applet)  
|LIGAND= <scene name='pdbligand=DBE:BIS(4-HYDROXYPHENYL)METHANONE'>DBE</scene>, <scene name='pdbligand=HEM:PROTOPORPHYRIN+IX+CONTAINING+FE'>HEM</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
|ACTIVITY= <span class='plainlinks'>[http://en.wikipedia.org/wiki/Sterol_14-demethylase Sterol 14-demethylase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.14.13.70 1.14.13.70] </span>
or leave the SCENE parameter empty for the default display.
|GENE=  
-->
|DOMAIN=<span class='plainlinks'>[http://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=pfam00067 p450]</span>
{{STRUCTURE_2vku| PDB=2vku  | SCENE= }}  
|RELATEDENTRY=[[1ea1|1EA1]], [[1u13|1U13]], [[2bz9|2BZ9]], [[2ci0|2CI0]], [[2cib|2CIB]], [[1e9x|1E9X]], [[1h5z|1H5Z]], [[1x8v|1X8V]]
|RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2vku FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2vku OCA], [http://www.ebi.ac.uk/pdbsum/2vku PDBsum], [http://www.rcsb.org/pdb/explore.do?structureId=2vku RCSB]</span>
}}


'''4,4'-DIHYDROXYBENZOPHENONE MIMICS STEROL SUBSTRATE IN THE BINDING SITE OF STEROL 14ALPHA-DEMETHYLASE (CYP51) IN THE X-RAY STRUCTURE OF THE COMPLEX'''
'''4,4'-DIHYDROXYBENZOPHENONE MIMICS STEROL SUBSTRATE IN THE BINDING SITE OF STEROL 14ALPHA-DEMETHYLASE (CYP51) IN THE X-RAY STRUCTURE OF THE COMPLEX'''
Line 25: Line 22:
[[Category: Podust, M V.]]
[[Category: Podust, M V.]]
[[Category: 4'- dihydroxybenzophenone complex]]
[[Category: 4'- dihydroxybenzophenone complex]]
[[Category: alpha-beta]]
[[Category: Alpha-beta]]
[[Category: cyp51-4]]
[[Category: Cyp51-4]]
[[Category: cytoplasm]]
[[Category: Cytoplasm]]
[[Category: heme]]
[[Category: Heme]]
[[Category: heme co-factor]]
[[Category: Heme co-factor]]
[[Category: iron]]
[[Category: Iron]]
[[Category: lipid synthesis]]
[[Category: Lipid synthesis]]
[[Category: metal-binding]]
[[Category: Metal-binding]]
[[Category: monooxygenase]]
[[Category: Monooxygenase]]
[[Category: nadp]]
[[Category: Nadp]]
[[Category: oxidoreductase]]
[[Category: Oxidoreductase]]
[[Category: steroid biosynthesis]]
[[Category: Steroid biosynthesis]]
[[Category: sterol biosynthesis]]
[[Category: Sterol biosynthesis]]
 
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sun May  4 18:58:13 2008''
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Mar 31 05:13:21 2008''

Revision as of 15:58, 4 May 2008

File:2vku.jpg

Template:STRUCTURE 2vku

4,4'-DIHYDROXYBENZOPHENONE MIMICS STEROL SUBSTRATE IN THE BINDING SITE OF STEROL 14ALPHA-DEMETHYLASE (CYP51) IN THE X-RAY STRUCTURE OF THE COMPLEX


About this Structure

2VKU is a Single protein structure of sequence from Mycobacterium tuberculosis. Full crystallographic information is available from OCA. Page seeded by OCA on Sun May 4 18:58:13 2008

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