6i52: Difference between revisions

Line 1:

~~'''Unreleased structure'''~~

~~The entry~~ 6i52 is ~~ON HOLD~~

==Yeast RPA bound to ssDNA==

~~Authors~~:

== Structural highlights ==

<table><tr><td colspan='2'>[[6i52]] is a 4 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6I52 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6I52 FirstGlance]. <br>

~~Description~~:

</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6i52 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6i52 OCA], [http://pdbe.org/6i52 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6i52 RCSB], [http://www.ebi.ac.uk/pdbsum/6i52 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6i52 ProSAT]</span></td></tr>

[[Category: ~~Unreleased Structures~~]]

</table>

== Function ==

[[http://www.uniprot.org/uniprot/RFA3_YEAST RFA3_YEAST]] As part of the replication protein A (RPA/RP-A), a single-stranded DNA-binding heterotrimeric complex, may play an essential role in DNA replication, recombination and repair. Binds and stabilizes single-stranded DNA intermediates, preventing complementary DNA reannealing and recruiting different proteins involved in DNA metabolism (By similarity). Stimulates the activity of a cognate strand exchange protein (SEP1). [[http://www.uniprot.org/uniprot/RFA1_YEAST RFA1_YEAST]] Binds to single-stranded sequences participating in DNA replication in addition to those mediating transcriptional repression (URS1) and activation (CAR1). Stimulates the activity of a cognate strand exchange protein (SEP1). It cooperates with T-AG and DNA topoisomerase I to unwind template DNA containing the simian virus 40 origin of DNA replication. [[http://www.uniprot.org/uniprot/RFA2_YEAST RFA2_YEAST]] Binds to single-stranded sequences participating in DNA replication in addition to those mediating transcriptional repression (URS1) and activation (CAR1). Stimulates the activity of a cognate strand exchange protein (SEP1). It cooperates with T-AG and DNA topoisomerase I to unwind template DNA containing the simian virus 40 origin of DNA replication.

__TOC__

</StructureSection>

[[Category: Aramayo, R J]]

[[Category: Yates, L A]]

[[Category: Zhang, X]]

[[Category: Complex]]

[[Category: Dna binding]]

[[Category: Dna binding protein]]

[[Category: Heterotrimer]]

[[Category: Ob-fold]]

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@@ Line 1: / Line 1: @@
-'''Unreleased structure'''
-The entry 6i52 is ON HOLD
+==Yeast RPA bound to ssDNA==
+<StructureSection load='6i52' size='340' side='right' caption='[[6i52]], [[Resolution|resolution]] 4.70&Aring;' scene=''>
-Authors:
+== Structural highlights ==
+<table><tr><td colspan='2'>[[6i52]] is a 4 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6I52 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6I52 FirstGlance]. <br>
-Description:
+</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6i52 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6i52 OCA], [http://pdbe.org/6i52 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6i52 RCSB], [http://www.ebi.ac.uk/pdbsum/6i52 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6i52 ProSAT]</span></td></tr>
-[[Category: Unreleased Structures]]
+</table>
+== Function ==
+[[http://www.uniprot.org/uniprot/RFA3_YEAST RFA3_YEAST]] As part of the replication protein A (RPA/RP-A), a single-stranded DNA-binding heterotrimeric complex, may play an essential role in DNA replication, recombination and repair. Binds and stabilizes single-stranded DNA intermediates, preventing complementary DNA reannealing and recruiting different proteins involved in DNA metabolism (By similarity). Stimulates the activity of a cognate strand exchange protein (SEP1). [[http://www.uniprot.org/uniprot/RFA1_YEAST RFA1_YEAST]] Binds to single-stranded sequences participating in DNA replication in addition to those mediating transcriptional repression (URS1) and activation (CAR1). Stimulates the activity of a cognate strand exchange protein (SEP1). It cooperates with T-AG and DNA topoisomerase I to unwind template DNA containing the simian virus 40 origin of DNA replication. [[http://www.uniprot.org/uniprot/RFA2_YEAST RFA2_YEAST]] Binds to single-stranded sequences participating in DNA replication in addition to those mediating transcriptional repression (URS1) and activation (CAR1). Stimulates the activity of a cognate strand exchange protein (SEP1). It cooperates with T-AG and DNA topoisomerase I to unwind template DNA containing the simian virus 40 origin of DNA replication.
+__TOC__
+</StructureSection>
+[[Category: Aramayo, R J]]
+[[Category: Yates, L A]]
+[[Category: Zhang, X]]
+[[Category: Complex]]
+[[Category: Dna binding]]
+[[Category: Dna binding protein]]
+[[Category: Heterotrimer]]
+[[Category: Ob-fold]]