6i8l: Difference between revisions

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'''Unreleased structure'''


The entry 6i8l is ON HOLD
==Crystal structure of Spindlin1 in complex with the inhibitor TD001851a==
 
<StructureSection load='6i8l' size='340' side='right' caption='[[6i8l]], [[Resolution|resolution]] 1.58&Aring;' scene=''>
Authors: Johansson, C., Fagan, V., Brennan, P.E., Sorrell, F.J., Krojer, T., Arrowsmith, C.H., Bountra, C., Edwards, A., Oppermann, U.C.T.
== Structural highlights ==
 
<table><tr><td colspan='2'>[[6i8l]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6I8L OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6I8L FirstGlance]. <br>
Description: Crystal structure of Spindlin1 in complex with the inhibitor TD001851a
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=DMS:DIMETHYL+SULFOXIDE'>DMS</scene>, <scene name='pdbligand=H7Q:5-(cyclopropylmethoxy)-6-[3-(1,3-dihydroisoindol-2-yl)propoxy]spiro[cyclopentane-1,3-indole]-2-amine'>H7Q</scene>, <scene name='pdbligand=MPD:(4S)-2-METHYL-2,4-PENTANEDIOL'>MPD</scene>, <scene name='pdbligand=MRD:(4R)-2-METHYLPENTANE-2,4-DIOL'>MRD</scene></td></tr>
[[Category: Unreleased Structures]]
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6i8l FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6i8l OCA], [http://pdbe.org/6i8l PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6i8l RCSB], [http://www.ebi.ac.uk/pdbsum/6i8l PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6i8l ProSAT]</span></td></tr>
[[Category: Arrowsmith, C.H]]
</table>
== Function ==
[[http://www.uniprot.org/uniprot/SPIN1_HUMAN SPIN1_HUMAN]] May play a role in cell-cycle regulation during the transition from gamete to embryo (By similarity).
__TOC__
</StructureSection>
[[Category: Arrowsmith, C H]]
[[Category: Bountra, C]]
[[Category: Brennan, P E]]
[[Category: Edwards, A]]
[[Category: Fagan, V]]
[[Category: Fagan, V]]
[[Category: Oppermann, U.C.T]]
[[Category: Johansson, C]]
[[Category: Johansson, C]]
[[Category: Brennan, P.E]]
[[Category: Edwards, A]]
[[Category: Krojer, T]]
[[Category: Krojer, T]]
[[Category: Bountra, C]]
[[Category: Oppermann, U C.T]]
[[Category: Sorrell, F.J]]
[[Category: Sorrell, F J]]
[[Category: Cell cycle]]
[[Category: Epigenetic]]
[[Category: Methyl-arginine]]
[[Category: Methyl-lysine]]
[[Category: Tudor domain]]
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