3f1s: Difference between revisions

From Proteopedia
Jump to navigationJump to search
← Older editNewer edit →
OCA (talk | contribs)
Bots, Bureaucrats, journal, Administrators
3,330,058 edits
No edit summary
OCA (talk | contribs)
Bots, Bureaucrats, journal, Administrators
3,330,058 edits
No edit summary
Line 1: Line 1:


==Crystal structure of Protein Z complexed with protein Z-dependent inhibitor==
==Crystal structure of Protein Z complexed with protein Z-dependent inhibitor==
<StructureSection load='3f1s' size='340' side='right' caption='[[3f1s]], [[Resolution|resolution]] 2.30&Aring;' scene=''>
<StructureSection load='3f1s' size='340' side='right'caption='[[3f1s]], [[Resolution|resolution]] 2.30&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[3f1s]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3F1S OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3F1S FirstGlance]. <br>
<table><tr><td colspan='2'>[[3f1s]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3F1S OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3F1S FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=FLC:CITRATE+ANION'>FLC</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene></td></tr>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=FLC:CITRATE+ANION'>FLC</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene></td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">SERPINA10, UNQ707/PRO1358, ZPI ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN]), PROZ, PZ ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">SERPINA10, UNQ707/PRO1358, ZPI ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN]), PROZ, PZ ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3f1s FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3f1s OCA], [http://pdbe.org/3f1s PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3f1s RCSB], [http://www.ebi.ac.uk/pdbsum/3f1s PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=3f1s ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3f1s FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3f1s OCA], [https://pdbe.org/3f1s PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3f1s RCSB], [https://www.ebi.ac.uk/pdbsum/3f1s PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3f1s ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[http://www.uniprot.org/uniprot/ZPI_HUMAN ZPI_HUMAN]] Inhibits activity of the coagulation protease factor Xa in the presence of PROZ, calcium and phospholipids. [[http://www.uniprot.org/uniprot/PROZ_HUMAN PROZ_HUMAN]] Appears to assist hemostasis by binding thrombin and promoting its association with phospholipid vesicles. Inhibits activity of the coagulation protease factor Xa in the presence of SERPINA10, calcium and phospholipids.  
[[https://www.uniprot.org/uniprot/ZPI_HUMAN ZPI_HUMAN]] Inhibits activity of the coagulation protease factor Xa in the presence of PROZ, calcium and phospholipids. [[https://www.uniprot.org/uniprot/PROZ_HUMAN PROZ_HUMAN]] Appears to assist hemostasis by binding thrombin and promoting its association with phospholipid vesicles. Inhibits activity of the coagulation protease factor Xa in the presence of SERPINA10, calcium and phospholipids.  
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
Line 31: Line 31:


==See Also==
==See Also==
*[[Serpin|Serpin]]
*[[Serpin 3D structures|Serpin 3D structures]]
== References ==
== References ==
<references/>
<references/>
Line 37: Line 37:
</StructureSection>
</StructureSection>
[[Category: Human]]
[[Category: Human]]
[[Category: Large Structures]]
[[Category: Zhou, A]]
[[Category: Zhou, A]]
[[Category: Blood coagulation]]
[[Category: Blood coagulation]]
Retrieved from "https://proteopedia.org/3f1s"