6imf: Difference between revisions
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==Crystal structure of TOXIN/ANTITOXIN complex== | |||
<StructureSection load='6imf' size='340' side='right' caption='[[6imf]], [[Resolution|resolution]] 2.30Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[6imf]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Protobothrops_flavoviridis Protobothrops flavoviridis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6IMF OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6IMF FirstGlance]. <br> | |||
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=MES:2-(N-MORPHOLINO)-ETHANESULFONIC+ACID'>MES</scene></td></tr> | |||
[[ | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6imf FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6imf OCA], [http://pdbe.org/6imf PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6imf RCSB], [http://www.ebi.ac.uk/pdbsum/6imf PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6imf ProSAT]</span></td></tr> | ||
[[ | </table> | ||
== Function == | |||
[[http://www.uniprot.org/uniprot/CRVP_PROFL CRVP_PROFL]] Blocks contraction of smooth muscle elicited by high potassium-induced depolarization (PubMed:12047379). May target voltage-gated calcium channels (Cav) on smooth muscle.<ref>PMID:12047379</ref> [[http://www.uniprot.org/uniprot/MSMB2_PROFL MSMB2_PROFL]] May serve as a self-defense protein against the toxic effects of the snake venom during accidental envenomation. Does not show inhibitory activity towards brevilysin H6. | |||
[[ | == References == | ||
[[ | <references/> | ||
[[Category: | __TOC__ | ||
</StructureSection> | |||
[[Category: Protobothrops flavoviridis]] | |||
[[Category: Hu, Y]] | [[Category: Hu, Y]] | ||
[[Category: Kita, S]] | [[Category: Kita, S]] | ||
[[Category: | [[Category: Kurahara, L H]] | ||
[[Category: Kuroki, K]] | |||
[[Category: Maenaka, K]] | [[Category: Maenaka, K]] | ||
[[Category: | [[Category: Matsubara, H]] | ||
[[Category: Okabe, Y]] | |||
[[Category: Ose, T]] | |||
[[Category: Shioi, N]] | |||
[[Category: Shioi, S]] | [[Category: Shioi, S]] | ||
[[Category: Tadokoro, T]] | |||
[[Category: Terada, S]] | |||
[[Category: Antitoxin]] | |||
[[Category: Complex]] | |||
[[Category: Toxin]] | |||
[[Category: Toxin-antitoxin complex]] | |||
Revision as of 06:55, 12 December 2018
Crystal structure of TOXIN/ANTITOXIN complex
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