3gx4: Difference between revisions

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==Crystal Structure Analysis of S. Pombe ATL in complex with DNA==
==Crystal Structure Analysis of S. Pombe ATL in complex with DNA==
<StructureSection load='3gx4' size='340' side='right' caption='[[3gx4]], [[Resolution|resolution]] 2.70&Aring;' scene=''>
<StructureSection load='3gx4' size='340' side='right'caption='[[3gx4]], [[Resolution|resolution]] 2.70&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[3gx4]] is a 3 chain structure with sequence from [http://en.wikipedia.org/wiki/Bcrc:21461 Bcrc:21461]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3GX4 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3GX4 FirstGlance]. <br>
<table><tr><td colspan='2'>[[3gx4]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Bcrc:21461 Bcrc:21461]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3GX4 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3GX4 FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=NCO:COBALT+HEXAMMINE(III)'>NCO</scene></td></tr>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=NCO:COBALT+HEXAMMINE(III)'>NCO</scene></td></tr>
<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=6OG:6-O-METHYL+GUANOSINE-5-MONOPHOSPHATE'>6OG</scene></td></tr>
<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=6OG:6-O-METHYL+GUANOSINE-5-MONOPHOSPHATE'>6OG</scene></td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[3gva|3gva]], [[3gyh|3gyh]]</td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[3gva|3gva]], [[3gyh|3gyh]]</div></td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">atl1, SPAC1250.04c ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=4896 BCRC:21461])</td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">atl1, SPAC1250.04c ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=4896 BCRC:21461])</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3gx4 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3gx4 OCA], [http://pdbe.org/3gx4 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3gx4 RCSB], [http://www.ebi.ac.uk/pdbsum/3gx4 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=3gx4 ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3gx4 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3gx4 OCA], [https://pdbe.org/3gx4 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3gx4 RCSB], [https://www.ebi.ac.uk/pdbsum/3gx4 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3gx4 ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[http://www.uniprot.org/uniprot/ATL1_SCHPO ATL1_SCHPO]] Acts as a DNA damage recognition factor. Required for DNA repair from mutagenic O(6)-alkylguanine adducts. Binds O(6)-alkylguanine lesions providing a signal for other DNA repair pathways.  
[[https://www.uniprot.org/uniprot/ATL1_SCHPO ATL1_SCHPO]] Acts as a DNA damage recognition factor. Required for DNA repair from mutagenic O(6)-alkylguanine adducts. Binds O(6)-alkylguanine lesions providing a signal for other DNA repair pathways.  
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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</StructureSection>
</StructureSection>
[[Category: Bcrc:21461]]
[[Category: Bcrc:21461]]
[[Category: Large Structures]]
[[Category: Arvai, A S]]
[[Category: Arvai, A S]]
[[Category: Tainer, J A]]
[[Category: Tainer, J A]]
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