5a8x: Difference between revisions

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==Crystal Structure of human neutrophil elastase in complex with a dihydropyrimidone inhibitor==
==Crystal Structure of human neutrophil elastase in complex with a dihydropyrimidone inhibitor==
<StructureSection load='5a8x' size='340' side='right' caption='[[5a8x]], [[Resolution|resolution]] 2.23&Aring;' scene=''>
<StructureSection load='5a8x' size='340' side='right'caption='[[5a8x]], [[Resolution|resolution]] 2.23&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[5a8x]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5A8X OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5A8X FirstGlance]. <br>
<table><tr><td colspan='2'>[[5a8x]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5A8X OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=5A8X FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=FUC:ALPHA-L-FUCOSE'>FUC</scene>, <scene name='pdbligand=IUY:ETHYL+(5R)-5-(4-CYANOPHENYL)-7-METHYL-8-[3-(TRIFLUOROMETHYL)PHENYL]-1,5-DIHYDROIMIDAZO[1,2-A]PYRIMIDIN-4-IUM-6-CARBOXYLATE'>IUY</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene></td></tr>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=IUY:ETHYL+(5R)-5-(4-CYANOPHENYL)-7-METHYL-8-[3-(TRIFLUOROMETHYL)PHENYL]-1,5-DIHYDROIMIDAZO[1,2-A]PYRIMIDIN-4-IUM-6-CARBOXYLATE'>IUY</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene>, <scene name='pdbligand=FUC:ALPHA-L-FUCOSE'>FUC</scene></td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[5a8y|5a8y]], [[5a8z|5a8z]]</td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[5a8y|5a8y]], [[5a8z|5a8z]]</td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Leukocyte_elastase Leukocyte elastase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.21.37 3.4.21.37] </span></td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Leukocyte_elastase Leukocyte elastase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.21.37 3.4.21.37] </span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5a8x FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5a8x OCA], [http://pdbe.org/5a8x PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5a8x RCSB], [http://www.ebi.ac.uk/pdbsum/5a8x PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5a8x ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=5a8x FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5a8x OCA], [http://pdbe.org/5a8x PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5a8x RCSB], [http://www.ebi.ac.uk/pdbsum/5a8x PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5a8x ProSAT]</span></td></tr>
</table>
</table>
== Disease ==
== Disease ==
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==See Also==
==See Also==
*[[Elastase|Elastase]]
*[[Elastase 3D structures|Elastase 3D structures]]
== References ==
== References ==
<references/>
<references/>
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</StructureSection>
</StructureSection>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Large Structures]]
[[Category: Leukocyte elastase]]
[[Category: Leukocyte elastase]]
[[Category: Anlauf, S]]
[[Category: Anlauf, S]]