5yxc: Difference between revisions

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==Crystal structure of Zinc binding protein ZinT in complex with citrate from E. coli==
==Crystal structure of Zinc binding protein ZinT in complex with citrate from E. coli==
<StructureSection load='5yxc' size='340' side='right' caption='[[5yxc]], [[Resolution|resolution]] 1.76&Aring;' scene=''>
<StructureSection load='5yxc' size='340' side='right'caption='[[5yxc]], [[Resolution|resolution]] 1.76&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[5yxc]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Ecoli Ecoli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5YXC OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5YXC FirstGlance]. <br>
<table><tr><td colspan='2'>[[5yxc]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli_K-12 Escherichia coli K-12]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5YXC OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5YXC FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CIT:CITRIC+ACID'>CIT</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.763&#8491;</td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">zinT, yodA, b1973, JW1956 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=83333 ECOLI])</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CIT:CITRIC+ACID'>CIT</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5yxc FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5yxc OCA], [http://pdbe.org/5yxc PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5yxc RCSB], [http://www.ebi.ac.uk/pdbsum/5yxc PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5yxc ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5yxc FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5yxc OCA], [https://pdbe.org/5yxc PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5yxc RCSB], [https://www.ebi.ac.uk/pdbsum/5yxc PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5yxc ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[http://www.uniprot.org/uniprot/ZINT_ECOLI ZINT_ECOLI]] May function as a periplasmic zinc chaperone or mediate direct transport of zinc from the periplasm to the cytoplasm under zinc-limited conditions. Binds zinc with high affinity, and can also bind cadmium, mercury or nickel. Preferentially binds Zn(2+) over Cd(2+). Contains one high affinity metal binding site, and can bind additional metal ions at other sites.<ref>PMID:17931600</ref> <ref>PMID:19377097</ref>
[https://www.uniprot.org/uniprot/ZINT_ECOLI ZINT_ECOLI] May function as a periplasmic zinc chaperone or mediate direct transport of zinc from the periplasm to the cytoplasm under zinc-limited conditions. Binds zinc with high affinity, and can also bind cadmium, mercury or nickel. Preferentially binds Zn(2+) over Cd(2+). Contains one high affinity metal binding site, and can bind additional metal ions at other sites.<ref>PMID:17931600</ref> <ref>PMID:19377097</ref>  
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Ecoli]]
[[Category: Escherichia coli K-12]]
[[Category: Chen, J]]
[[Category: Large Structures]]
[[Category: Shang, F]]
[[Category: Chen J]]
[[Category: Wang, L]]
[[Category: Shang F]]
[[Category: Xu, Y]]
[[Category: Wang L]]
[[Category: Citrate]]
[[Category: Xu Y]]
[[Category: Complex]]
[[Category: Metal binding protein]]
[[Category: Zinc binding protein]]