3bgl: Difference between revisions

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[[Image:3bgl.jpg|left|200px]]
[[Image:3bgl.jpg|left|200px]]


{{Structure
<!--
|PDB= 3bgl |SIZE=350|CAPTION= <scene name='initialview01'>3bgl</scene>, resolution 2.225&Aring;
The line below this paragraph, containing "STRUCTURE_3bgl", creates the "Structure Box" on the page.
|SITE= <scene name='pdbsite=AC1:Rid+Binding+Site+For+Residue+A+2'>AC1</scene>, <scene name='pdbsite=AC2:Rid+Binding+Site+For+Residue+B+1'>AC2</scene>, <scene name='pdbsite=AC3:Rid+Binding+Site+For+Residue+C+4'>AC3</scene> and <scene name='pdbsite=AC4:Rid+Binding+Site+For+Residue+D+3'>AC4</scene>
You may change the PDB parameter (which sets the PDB file loaded into the applet)  
|LIGAND= <scene name='pdbligand=RID:(3R,5R)-7-[2-(4-FLUOROPHENYL)-5-(1-METHYLETHYL)-4-(MORPHOLIN-4-YLSULFONYL)-3-PHENYL-1H-PYRROL-1-YL]-3,5-DIHYDROXYHEPTANOIC+ACID'>RID</scene>
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
|ACTIVITY= <span class='plainlinks'>[http://en.wikipedia.org/wiki/Hydroxymethylglutaryl-CoA_reductase_(NADPH) Hydroxymethylglutaryl-CoA reductase (NADPH)], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.1.1.34 1.1.1.34] </span>
or leave the SCENE parameter empty for the default display.
|GENE= HMGCR ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens])
-->
|DOMAIN=
{{STRUCTURE_3bgl| PDB=3bgl  | SCENE= }}  
|RELATEDENTRY=[[2q1l|2Q1L]], [[2q6b|2Q6B]], [[2q6c|2Q6C]], [[2r4f|2R4F]]
|RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3bgl FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3bgl OCA], [http://www.ebi.ac.uk/pdbsum/3bgl PDBsum], [http://www.rcsb.org/pdb/explore.do?structureId=3bgl RCSB]</span>
}}


'''Hepatoselectivity of Statins: Design and synthesis of 4-sulfamoyl pyrroles as HMG-CoA reductase inhibitors'''
'''Hepatoselectivity of Statins: Design and synthesis of 4-sulfamoyl pyrroles as HMG-CoA reductase inhibitors'''
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Hepatoselectivity of statins: design and synthesis of 4-sulfamoyl pyrroles as HMG-CoA reductase inhibitors., Park WK, Kennedy RM, Larsen SD, Miller S, Roth BD, Song Y, Steinbaugh BA, Sun K, Tait BD, Kowala MC, Trivedi BK, Auerbach B, Askew V, Dillon L, Hanselman JC, Lin Z, Lu GH, Robertson A, Sekerke C, Bioorg Med Chem Lett. 2008 Feb 1;18(3):1151-6. Epub 2007 Dec 5. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/18155906 18155906]
Hepatoselectivity of statins: design and synthesis of 4-sulfamoyl pyrroles as HMG-CoA reductase inhibitors., Park WK, Kennedy RM, Larsen SD, Miller S, Roth BD, Song Y, Steinbaugh BA, Sun K, Tait BD, Kowala MC, Trivedi BK, Auerbach B, Askew V, Dillon L, Hanselman JC, Lin Z, Lu GH, Robertson A, Sekerke C, Bioorg Med Chem Lett. 2008 Feb 1;18(3):1151-6. Epub 2007 Dec 5. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/18155906 18155906]
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Hydroxymethylglutaryl-CoA reductase (NADPH)]]
[[Category: Single protein]]
[[Category: Single protein]]
[[Category: Finzel, B C.]]
[[Category: Finzel, B C.]]
[[Category: Park, W K.C.]]
[[Category: Park, W K.C.]]
[[Category: Pavlovsky, A.]]
[[Category: Pavlovsky, A.]]
[[Category: alternative splicing]]
[[Category: Alternative splicing]]
[[Category: cholesterol biosynthesis]]
[[Category: Cholesterol biosynthesis]]
[[Category: endoplasmic reticulum]]
[[Category: Endoplasmic reticulum]]
[[Category: glycoprotein]]
[[Category: Glycoprotein]]
[[Category: hmg-coa]]
[[Category: Hmg-coa]]
[[Category: lipid synthesis]]
[[Category: Lipid synthesis]]
[[Category: membrane]]
[[Category: Membrane]]
[[Category: nadph]]
[[Category: Nadph]]
[[Category: oxidoreductase]]
[[Category: Oxidoreductase]]
[[Category: peroxisome]]
[[Category: Peroxisome]]
[[Category: polymorphism]]
[[Category: Polymorphism]]
[[Category: statin]]
[[Category: Statin]]
[[Category: steroid biosynthesis]]
[[Category: Steroid biosynthesis]]
[[Category: transmembrane]]
[[Category: Transmembrane]]
 
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Apr 30 13:38:36 2008''
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Mar 31 05:26:02 2008''
Retrieved from "https://proteopedia.org/3bgl"