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==Crystal structure of Mycobacterium tuberculosis HtrA1 (Rv1223) in regulated conformation==
==Crystal structure of Mycobacterium tuberculosis HtrA1 (Rv1223) in regulated conformation==
<StructureSection load='6ieo' size='340' side='right' caption='[[6ieo]], [[Resolution|resolution]] 1.83&Aring;' scene=''>
<StructureSection load='6ieo' size='340' side='right'caption='[[6ieo]], [[Resolution|resolution]] 1.83&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[6ieo]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6IEO OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6IEO FirstGlance]. <br>
<table><tr><td colspan='2'>[[6ieo]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Mycobacterium_tuberculosis_H37Rv Mycobacterium tuberculosis H37Rv]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6IEO OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6IEO FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=PMS:PHENYLMETHANESULFONIC+ACID'>PMS</scene></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.83&#8491;</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6ieo FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6ieo OCA], [http://pdbe.org/6ieo PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6ieo RCSB], [http://www.ebi.ac.uk/pdbsum/6ieo PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6ieo ProSAT]</span></td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=PMS:PHENYLMETHANESULFONIC+ACID'>PMS</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6ieo FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6ieo OCA], [https://pdbe.org/6ieo PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6ieo RCSB], [https://www.ebi.ac.uk/pdbsum/6ieo PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6ieo ProSAT]</span></td></tr>
</table>
</table>
== Function ==
[https://www.uniprot.org/uniprot/HTRA1_MYCTU HTRA1_MYCTU] Essential protein that may act as a regulatory protease that is conditionally activated upon appropriate environmental triggers.<ref>PMID:30511675</ref>
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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==See Also==
==See Also==
*[[Journal:Acta Cryst F:S2053230X18016217|Journal:Acta Cryst F:S2053230X18016217]]
*[[Proteins from Mycobacterium tuberculosis|Proteins from Mycobacterium tuberculosis]]
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Gopal, B]]
[[Category: Large Structures]]
[[Category: Gupta, A K]]
[[Category: Mycobacterium tuberculosis H37Rv]]
[[Category: Chymotrypsin like]]
[[Category: Gopal B]]
[[Category: Htra family of serine protease]]
[[Category: Gupta AK]]
[[Category: Hydrolase]]
[[Category: Membrane protein]]
[[Category: Periplasm]]
[[Category: Protein quality control and signal transduction]]
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