5xt4: Difference between revisions

From Proteopedia
Jump to navigationJump to search
OCA (talk | contribs)
No edit summary
OCA (talk | contribs)
No edit summary
 
Line 1: Line 1:


==Crystal Structure of Transketolase in complex with TPP intermediate VIII' from Pichia Stipitis==
==Crystal Structure of Transketolase in complex with TPP intermediate VIII' from Pichia Stipitis==
<StructureSection load='5xt4' size='340' side='right' caption='[[5xt4]], [[Resolution|resolution]] 1.06&Aring;' scene=''>
<StructureSection load='5xt4' size='340' side='right'caption='[[5xt4]], [[Resolution|resolution]] 1.06&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[5xt4]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Picst Picst]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5XT4 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5XT4 FirstGlance]. <br>
<table><tr><td colspan='2'>[[5xt4]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Scheffersomyces_stipitis_CBS_6054 Scheffersomyces stipitis CBS 6054]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5XT4 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5XT4 FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=PEG:DI(HYDROXYETHYL)ETHER'>PEG</scene>, <scene name='pdbligand=T6F:2-C-{3-[(4-AMINO-2-METHYLPYRIMIDIN-5-YL)METHYL]-5-(2-{[(R)-HYDROXY(PHOSPHONOOXY)PHOSPHORYL]OXY}ETHYL)-4-METHYL-1,3-THIAZOL-3-IUM-2-YL}-6-O-PHOSPHONO-D-GLUCITOL'>T6F</scene></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.06&#8491;</td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">TKT, TKT1, PICST_67105 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=322104 PICST])</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=PEG:DI(HYDROXYETHYL)ETHER'>PEG</scene>, <scene name='pdbligand=T6F:2-C-{3-[(4-AMINO-2-METHYLPYRIMIDIN-5-YL)METHYL]-5-(2-{[(R)-HYDROXY(PHOSPHONOOXY)PHOSPHORYL]OXY}ETHYL)-4-METHYL-1,3-THIAZOL-3-IUM-2-YL}-6-O-PHOSPHONO-D-GLUCITOL'>T6F</scene></td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Transketolase Transketolase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.2.1.1 2.2.1.1] </span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5xt4 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5xt4 OCA], [https://pdbe.org/5xt4 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5xt4 RCSB], [https://www.ebi.ac.uk/pdbsum/5xt4 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5xt4 ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5xt4 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5xt4 OCA], [http://pdbe.org/5xt4 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5xt4 RCSB], [http://www.ebi.ac.uk/pdbsum/5xt4 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5xt4 ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[http://www.uniprot.org/uniprot/TKT_PICST TKT_PICST]] Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate.  
[https://www.uniprot.org/uniprot/TKT_PICST TKT_PICST] Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate.
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
Line 22: Line 21:


==See Also==
==See Also==
*[[Transketolase|Transketolase]]
*[[Transketolase 3D structures|Transketolase 3D structures]]
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Picst]]
[[Category: Large Structures]]
[[Category: Transketolase]]
[[Category: Scheffersomyces stipitis CBS 6054]]
[[Category: Hsu, N S]]
[[Category: Hsu NS]]
[[Category: Li, T L]]
[[Category: Li TL]]
[[Category: Wang, Y L]]
[[Category: Wang YL]]
[[Category: Transferase]]

Latest revision as of 08:13, 22 November 2023

Crystal Structure of Transketolase in complex with TPP intermediate VIII' from Pichia Stipitis

5xt4, resolution 1.06Å

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA