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==Crystal structure of Xylose reductase from Debaryomyces nepalensis in complex with NADP-DTT adduct==
==Crystal structure of Xylose reductase from Debaryomyces nepalensis in complex with NADP-DTT adduct==
<StructureSection load='5zcm' size='340' side='right' caption='[[5zcm]], [[Resolution|resolution]] 1.70&Aring;' scene=''>
<StructureSection load='5zcm' size='340' side='right'caption='[[5zcm]], [[Resolution|resolution]] 1.70&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[5zcm]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Atcc_22463 Atcc 22463]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5ZCM OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5ZCM FirstGlance]. <br>
<table><tr><td colspan='2'>[[5zcm]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Debaryomyces_nepalensis Debaryomyces nepalensis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5ZCM OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5ZCM FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=DTT:2,3-DIHYDROXY-1,4-DITHIOBUTANE'>DTT</scene>, <scene name='pdbligand=NDP:NADPH+DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE+PHOSPHATE'>NDP</scene></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.7&#8491;</td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">AR ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=27299 ATCC 22463])</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=DTT:2,3-DIHYDROXY-1,4-DITHIOBUTANE'>DTT</scene>, <scene name='pdbligand=NDP:NADPH+DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE+PHOSPHATE'>NDP</scene></td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Aldehyde_reductase Aldehyde reductase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.1.1.21 1.1.1.21] </span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5zcm FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5zcm OCA], [https://pdbe.org/5zcm PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5zcm RCSB], [https://www.ebi.ac.uk/pdbsum/5zcm PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5zcm ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5zcm FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5zcm OCA], [http://pdbe.org/5zcm PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5zcm RCSB], [http://www.ebi.ac.uk/pdbsum/5zcm PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5zcm ProSAT]</span></td></tr>
</table>
</table>
== Function ==
[https://www.uniprot.org/uniprot/A0A0M4HL56_9ASCO A0A0M4HL56_9ASCO]
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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</div>
</div>
<div class="pdbe-citations 5zcm" style="background-color:#fffaf0;"></div>
<div class="pdbe-citations 5zcm" style="background-color:#fffaf0;"></div>
==See Also==
*[[Aldose reductase 3D structures|Aldose reductase 3D structures]]
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Aldehyde reductase]]
[[Category: Debaryomyces nepalensis]]
[[Category: Atcc 22463]]
[[Category: Large Structures]]
[[Category: Manoj, N]]
[[Category: Manoj N]]
[[Category: Aldo-keto reductase]]
[[Category: Carbohydrate metabolism]]
[[Category: Oxidoreductase]]
[[Category: Tim barrel]]
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