Sandbox Reserved 1482: Difference between revisions

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	“Factor VIII” is an inactive form. The Factor VIII circulates in the bloodstream in this inactive form, bound to another molecule called ~~von~~ Willebrand ~~factor~~, until an injury that damages blood vessels occurs. Indeed, in plasma, factor VIII exists in two forms: free or as a complex with the von Willebrand factor. The complex is the predominant form and exists at a concentration of 0.1 µg/ml in the blood because factor VIII is stabilized by von Willebrand factor, while in its free state, it is rapidly cleaved by protease serines <sup>[8,14]</sup>.		“Factor VIII” is an inactive form. The Factor VIII circulates in the bloodstream in this inactive form, bound to another molecule called [[Von Willebrand Factor]], until an injury that damages blood vessels occurs. Indeed, in plasma, factor VIII exists in two forms: free or as a complex with the von Willebrand factor. The complex is the predominant form and exists at a concentration of 0.1 µg/ml in the blood because factor VIII is stabilized by von Willebrand factor, while in its free state, it is rapidly cleaved by protease serines <sup>[8,14]</sup>.

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