Base stacking: Difference between revisions
From Proteopedia
Jump to navigationJump to search
No edit summary |
No edit summary |
||
| Line 6: | Line 6: | ||
# '''DNA double helix''': In <scene name='80/804504/Dna/3'>double-stranded DNA</scene>, bases from two strands pair up to form base pairs, which are stacked along the helix axis of the double strand. Zooming in to a detailed view of a <scene name='80/804504/Dna/5'>G:C base pair</scene>, the extent of the stacking contacts are determined by the sequence. G:C base pairs contribute more to the thermal stability of DNA than A:T base pairs because they stack better. | # '''DNA double helix''': In <scene name='80/804504/Dna/3'>double-stranded DNA</scene>, bases from two strands pair up to form base pairs, which are stacked along the helix axis of the double strand. Zooming in to a detailed view of a <scene name='80/804504/Dna/5'>G:C base pair</scene>, the extent of the stacking contacts are determined by the sequence. G:C base pairs contribute more to the thermal stability of DNA than A:T base pairs because they stack better. | ||
# '''RNA kissing loops''': Loops on two separate RNA pieces are held together by <scene name='80/804504/Kissing_loop/ | # '''RNA kissing loops''': Loops on two separate RNA pieces are held together by <scene name='80/804504/Kissing_loop/5'>stacking interactions</scene> (between base pairs) and<scene name='80/804504/Kissing_loop/4'> hydrogen bonds</scene> (within base pairs). | ||
# '''RNA single strand bound to a protein''': In this <scene name='80/804504/Intercalation/ | # '''RNA single strand bound to a protein''': In this <scene name='80/804504/Intercalation/6'>complex of RNA bound to a protein</scene>, some of the stacking interactions are disrupted by amino acid side chains (such as arginine, histidine and tyrosine) intercalating between adjacent bases. <jmol> | ||
<jmolRadioGroup> | <jmolRadioGroup> | ||
<item> | <item> | ||
