6n7e: Difference between revisions

Line 1:

~~'''Unreleased structure'''~~

~~The entry~~ 6n7e is ~~ON HOLD until Paper Publication~~

==Crystal structure of the cytosolic domain of human CNNM2 in complex with AMP-PNP and Mg2+==

~~Authors~~:

== Structural highlights ==

<table><tr><td colspan='2'>[[6n7e]] is a 4 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6N7E OCA]. For a guided tour on the structure components use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6N7E FirstGlance].

~~Description~~:

</td></tr><tr id='ligand'><td class="sblockLbl">[[Ligand|Ligands:]]</td><td class="sblockDat"><scene name='pdbligand=ANP:PHOSPHOAMINOPHOSPHONIC+ACID-ADENYLATE+ESTER'>ANP</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>

[[Category: ~~Unreleased~~ Structures]]

<tr id='related'><td class="sblockLbl">[[Related_structure|Related:]]</td><td class="sblockDat">[[6mn6|6mn6]]</td></tr>

<tr id='resources'><td class="sblockLbl">Resources:</td><td class="sblockDat">[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6n7e FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6n7e OCA], [http://pdbe.org/6n7e PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6n7e RCSB], [http://www.ebi.ac.uk/pdbsum/6n7e PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6n7e ProSAT]</td></tr>

</table>

== Disease ==

[[http://www.uniprot.org/uniprot/CNNM2_HUMAN CNNM2_HUMAN]] Familial primary hypomagnesemia with normocalcuria and normocalcemia. The disease is caused by mutations affecting the gene represented in this entry.

== Function ==

[[http://www.uniprot.org/uniprot/CNNM2_HUMAN CNNM2_HUMAN]] Divalent metal cation transporter. Mediates transport of divalent metal cations in an order of Mg(2+) > Co(2+) > Mn(2+) > Sr(2+) > Ba(2+) > Cu(2+) > Fe(2+) (By similarity).

__TOC__

</StructureSection>

[[Category: Large Structures]]

[[Category: Chen, Y S]]

[[Category: Gehring, K]]

[[Category: Atp-bound]]

[[Category: Closed conformation]]

[[Category: Cnnm2]]

[[Category: Cyclic nucleotide-binding homology domain]]

[[Category: Cystathionine-beta-synthase domain]]

[[Category: Membrane protein]]

[[Category: Metal transport]]

[[Category: Mg2+ transporter]]

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@@ Line 1: / Line 1: @@
-'''Unreleased structure'''
-The entry 6n7e is ON HOLD  until Paper Publication
+==Crystal structure of the cytosolic domain of human CNNM2 in complex with AMP-PNP and Mg2+==
+<StructureSection load='6n7e' size='340' side='right'caption='[[6n7e]], [[Resolution|resolution]] 3.50&Aring;' scene=''>
-Authors:
+== Structural highlights ==
+<table><tr><td colspan='2'>[[6n7e]] is a 4 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6N7E OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6N7E FirstGlance]. <br>
-Description:
+</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ANP:PHOSPHOAMINOPHOSPHONIC+ACID-ADENYLATE+ESTER'>ANP</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
-[[Category: Unreleased Structures]]
+<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[6mn6|6mn6]]</td></tr>
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6n7e FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6n7e OCA], [http://pdbe.org/6n7e PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6n7e RCSB], [http://www.ebi.ac.uk/pdbsum/6n7e PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6n7e ProSAT]</span></td></tr>
+</table>
+== Disease ==
+[[http://www.uniprot.org/uniprot/CNNM2_HUMAN CNNM2_HUMAN]] Familial primary hypomagnesemia with normocalcuria and normocalcemia. The disease is caused by mutations affecting the gene represented in this entry.
+== Function ==
+[[http://www.uniprot.org/uniprot/CNNM2_HUMAN CNNM2_HUMAN]] Divalent metal cation transporter. Mediates transport of divalent metal cations in an order of Mg(2+) > Co(2+) > Mn(2+) > Sr(2+) > Ba(2+) > Cu(2+) > Fe(2+) (By similarity).
+__TOC__
+</StructureSection>
+[[Category: Large Structures]]
+[[Category: Chen, Y S]]
+[[Category: Gehring, K]]
+[[Category: Atp-bound]]
+[[Category: Closed conformation]]
+[[Category: Cnnm2]]
+[[Category: Cyclic nucleotide-binding homology domain]]
+[[Category: Cystathionine-beta-synthase domain]]
+[[Category: Membrane protein]]
+[[Category: Metal transport]]
+[[Category: Mg2+ transporter]]