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==High resolution crystal structure of transketolase from Campylobacter jejuni subsp. jejuni NCTC 11168==
==High resolution crystal structure of transketolase from Campylobacter jejuni subsp. jejuni NCTC 11168==
<StructureSection load='3l84' size='340' side='right' caption='[[3l84]], [[Resolution|resolution]] 1.36&Aring;' scene=''>
<StructureSection load='3l84' size='340' side='right'caption='[[3l84]], [[Resolution|resolution]] 1.36&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[3l84]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Camje Camje]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3L84 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3L84 FirstGlance]. <br>
<table><tr><td colspan='2'>[[3l84]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Campylobacter_jejuni_subsp._jejuni_NCTC_11168_=_ATCC_700819 Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3L84 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3L84 FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.36&#8491;</td></tr>
<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">tkt, Cj1645 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=192222 CAMJE])</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3l84 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3l84 OCA], [https://pdbe.org/3l84 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3l84 RCSB], [https://www.ebi.ac.uk/pdbsum/3l84 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3l84 ProSAT]</span></td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Transketolase Transketolase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.2.1.1 2.2.1.1] </span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3l84 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3l84 OCA], [http://pdbe.org/3l84 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3l84 RCSB], [http://www.ebi.ac.uk/pdbsum/3l84 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=3l84 ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[http://www.uniprot.org/uniprot/Q0P7Y3_CAMJE Q0P7Y3_CAMJE]] Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate (By similarity).[RuleBase:RU004996]  
[https://www.uniprot.org/uniprot/Q0P7Y3_CAMJE Q0P7Y3_CAMJE] Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate (By similarity).[RuleBase:RU004996]
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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   <jmolCheckbox>
   <jmolCheckbox>
     <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/l8/3l84_consurf.spt"</scriptWhenChecked>
     <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/l8/3l84_consurf.spt"</scriptWhenChecked>
     <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
     <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview03.spt</scriptWhenUnchecked>
     <text>to colour the structure by Evolutionary Conservation</text>
     <text>to colour the structure by Evolutionary Conservation</text>
   </jmolCheckbox>
   </jmolCheckbox>
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==See Also==
==See Also==
*[[Transketolase|Transketolase]]
*[[Transketolase 3D structures|Transketolase 3D structures]]
__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Camje]]
[[Category: Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819]]
[[Category: Transketolase]]
[[Category: Large Structures]]
[[Category: Anderson, W]]
[[Category: Anderson W]]
[[Category: Structural genomic]]
[[Category: Grimshaw S]]
[[Category: Grimshaw, S]]
[[Category: Joachimiak A]]
[[Category: Joachimiak, A]]
[[Category: Makowska-Grzyska M]]
[[Category: Makowska-Grzyska, M]]
[[Category: Maltseva N]]
[[Category: Maltseva, N]]
[[Category: Nocek B]]
[[Category: Nocek, B]]
[[Category: Csgid]]
[[Category: Tkt]]
[[Category: Transferase]]
Retrieved from "https://proteopedia.org/3l84"