2cf8: Difference between revisions

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==Complex of recombinant human thrombin with an inhibitor==
==Complex of recombinant human thrombin with an inhibitor==
<StructureSection load='2cf8' size='340' side='right' caption='[[2cf8]], [[Resolution|resolution]] 1.30&Aring;' scene=''>
<StructureSection load='2cf8' size='340' side='right'caption='[[2cf8]], [[Resolution|resolution]] 1.30&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[2cf8]] is a 3 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2CF8 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2CF8 FirstGlance]. <br>
<table><tr><td colspan='2'>[[2cf8]] is a 3 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2CF8 OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=2CF8 FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=ESH:4-+[(1R,3AS,4R,8AS,8BR)-+2-+(4-CHLOROBENZYL)-+1-+ISOPROPYL-+3-+OXODECAHYDROPYRROLO[3,4-+A]PYRROLIZIN-+4-+YL]BENZENECARBOXIMIDAMIDE'>ESH</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene></td></tr>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=ESH:4-+[(1R,3AS,4R,8AS,8BR)-+2-+(4-CHLOROBENZYL)-+1-+ISOPROPYL-+3-+OXODECAHYDROPYRROLO[3,4-+A]PYRROLIZIN-+4-+YL]BENZENECARBOXIMIDAMIDE'>ESH</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene></td></tr>
<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=SIN:SUCCINIC+ACID'>SIN</scene></td></tr>
<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=SIN:SUCCINIC+ACID'>SIN</scene></td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[2cf9|2cf9]]</td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[2cf9|2cf9]]</td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Thrombin Thrombin], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.21.5 3.4.21.5] </span></td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Thrombin Thrombin], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.21.5 3.4.21.5] </span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2cf8 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2cf8 OCA], [http://pdbe.org/2cf8 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2cf8 RCSB], [http://www.ebi.ac.uk/pdbsum/2cf8 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2cf8 ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=2cf8 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2cf8 OCA], [http://pdbe.org/2cf8 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2cf8 RCSB], [http://www.ebi.ac.uk/pdbsum/2cf8 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2cf8 ProSAT]</span></td></tr>
</table>
</table>
== Disease ==
== Disease ==
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==See Also==
==See Also==
*[[Hirudin|Hirudin]]
*[[Hirudin 3D structures|Hirudin 3D structures]]
*[[Thrombin|Thrombin]]
*[[Thrombin 3D Structures|Thrombin 3D Structures]]
== References ==
== References ==
<references/>
<references/>
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</StructureSection>
</StructureSection>
[[Category: Human]]
[[Category: Human]]
[[Category: Large Structures]]
[[Category: Thrombin]]
[[Category: Thrombin]]
[[Category: Banner, D W]]
[[Category: Banner, D W]]