6qck: Difference between revisions
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==17beta-hydroxysteroid dehydrogenase 14 variant T205 in complex with FB262== | |||
<StructureSection load='6qck' size='340' side='right'caption='[[6qck]], [[Resolution|resolution]] 1.68Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[6qck]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6QCK OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6QCK FirstGlance]. <br> | |||
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=BGC:BETA-D-GLUCOSE'>BGC</scene>, <scene name='pdbligand=DMS:DIMETHYL+SULFOXIDE'>DMS</scene>, <scene name='pdbligand=HWK:2-[2-(1,3-benzodioxol-2-yl)ethyl]benzoic+acid'>HWK</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=NAD:NICOTINAMIDE-ADENINE-DINUCLEOTIDE'>NAD</scene></td></tr> | |||
[[Category: | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6qck FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6qck OCA], [http://pdbe.org/6qck PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6qck RCSB], [http://www.ebi.ac.uk/pdbsum/6qck PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6qck ProSAT]</span></td></tr> | ||
</table> | |||
== Function == | |||
[[http://www.uniprot.org/uniprot/DHB14_HUMAN DHB14_HUMAN]] Has NAD-dependent 17-beta-hydroxysteroid dehydrogenase activity. Converts oestradiol to oestrone. The physiological substrate is not known. Acts on oestradiol and 5-androstene-3-beta,17-beta-diol (in vitro).<ref>PMID:17067289</ref> | |||
== References == | |||
<references/> | |||
__TOC__ | |||
</StructureSection> | |||
[[Category: Large Structures]] | |||
[[Category: Bertoletti, N]] | |||
[[Category: Heine, A]] | [[Category: Heine, A]] | ||
[[Category: | [[Category: Klebe, G]] | ||
[[Category: Marchais-Oberwinkler, S]] | [[Category: Marchais-Oberwinkler, S]] | ||
[[Category: | [[Category: 17b-hsd14]] | ||
[[Category: Fragment]] | |||
[[Category: Oxidoreductase]] | |||
[[Category: Soaking]] | |||
Revision as of 15:35, 29 January 2020
17beta-hydroxysteroid dehydrogenase 14 variant T205 in complex with FB262
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