465d: Difference between revisions

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[[Image:465d.gif|left|200px]]
[[Image:465d.gif|left|200px]]


{{Structure
<!--
|PDB= 465d |SIZE=350|CAPTION= <scene name='initialview01'>465d</scene>, resolution 1.6&Aring;
The line below this paragraph, containing "STRUCTURE_465d", creates the "Structure Box" on the page.
|SITE=
You may change the PDB parameter (which sets the PDB file loaded into the applet)
|LIGAND= <scene name='pdbligand=9AD:9-AMINO-(N-(2-DIMETHYLAMINO)ETHYL)ACRIDINE-4-CARBOXAMIDE'>9AD</scene>, <scene name='pdbligand=DA:2&#39;-DEOXYADENOSINE-5&#39;-MONOPHOSPHATE'>DA</scene>, <scene name='pdbligand=DC:2&#39;-DEOXYCYTIDINE-5&#39;-MONOPHOSPHATE'>DC</scene>, <scene name='pdbligand=DG:2&#39;-DEOXYGUANOSINE-5&#39;-MONOPHOSPHATE'>DG</scene>, <scene name='pdbligand=DT:THYMIDINE-5&#39;-MONOPHOSPHATE'>DT</scene>
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
|ACTIVITY=  
or leave the SCENE parameter empty for the default display.
|GENE=  
-->
|DOMAIN=
{{STRUCTURE_465d| PDB=465d  | SCENE= }}  
|RELATEDENTRY=
|RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=465d FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=465d OCA], [http://www.ebi.ac.uk/pdbsum/465d PDBsum], [http://www.rcsb.org/pdb/explore.do?structureId=465d RCSB]</span>
}}


'''STRUCTURE OF THE TOPOISOMERASE II POISON BOUND TO DNA'''
'''STRUCTURE OF THE TOPOISOMERASE II POISON BOUND TO DNA'''
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==About this Structure==
==About this Structure==
465D is a [[Protein complex]] structure of sequences from [http://en.wikipedia.org/wiki/ ]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=465D OCA].  
Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=465D OCA].  


==Reference==
==Reference==
Crystal structure of the topoisomerase II poison 9-amino-[N-(2-dimethylamino)ethyl]acridine-4-carboxamide bound to the DNA hexanucleotide d(CGTACG)2., Adams A, Guss JM, Collyer CA, Denny WA, Wakelin LP, Biochemistry. 1999 Jul 20;38(29):9221-33. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/10413496 10413496]
Crystal structure of the topoisomerase II poison 9-amino-[N-(2-dimethylamino)ethyl]acridine-4-carboxamide bound to the DNA hexanucleotide d(CGTACG)2., Adams A, Guss JM, Collyer CA, Denny WA, Wakelin LP, Biochemistry. 1999 Jul 20;38(29):9221-33. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/10413496 10413496]
[[Category: Protein complex]]
[[Category: Adams, A.]]
[[Category: Adams, A.]]
[[Category: Collyer, C A.]]
[[Category: Collyer, C A.]]
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[[Category: Wakelin, L P.]]
[[Category: Wakelin, L P.]]
[[Category: 9-amino-daca]]
[[Category: 9-amino-daca]]
[[Category: d(cgtacg)2]]
[[Category: Hexanucleotide]]
[[Category: hexanucleotide]]
[[Category: Topoisomerase ii poison]]
[[Category: topoisomerase ii poison]]
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