Sandbox Reserved 1482: Difference between revisions
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The light chain has a molecular weight of 80 kDa and is composed of 684 amino acids <sup>[3]</sup>. It contains two domains: a unique A domain of 371 amino acids and a duplicated C domain of 153 amino acids and 160 amino acids, respectively <sup>[3]</sup>. These domains are ranked in the following order A<sub>3</sub>-C<sub>1</sub>-C<sub>2</sub> <sup>[3,8]</sup>. It is composed of 42 % irregular structure, 36 % β-strands, and 22 % α-helices <sup>[3]</sup>. The C<sub>1</sub> and C<sub>2</sub> domains are defined by a distorted β barrel, while A<sub>3</sub>, as well as A<sub>1</sub> and A<sub>2</sub>, is composed of two connected β barrels <sup>[9]</sup>. This chain also contains of the major binding site of von Willebrand Factor at its N-terminus <sup>[3]</sup>. | The <scene name='80/802656/Light_chain/1'>light chain</scene> has a molecular weight of 80 kDa and is composed of 684 amino acids <sup>[3]</sup>. It contains two domains: a unique A domain of 371 amino acids and a duplicated C domain of 153 amino acids and 160 amino acids, respectively <sup>[3]</sup>. These domains are ranked in the following order A<sub>3</sub>-C<sub>1</sub>-C<sub>2</sub> <sup>[3,8]</sup>. It is composed of 42 % irregular structure, 36 % β-strands, and 22 % α-helices <sup>[3]</sup>. The C<sub>1</sub> and C<sub>2</sub> domains are defined by a distorted β barrel, while A<sub>3</sub>, as well as A<sub>1</sub> and A<sub>2</sub>, is composed of two connected β barrels <sup>[9]</sup>. This chain also contains of the major binding site of von Willebrand Factor at its N-terminus <sup>[3]</sup>. | ||
