Sandbox Reserved 1485: Difference between revisions
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==2RO1 (KAP-1)== | ==2RO1 (KAP-1)== | ||
KAP-1 (KRAB – associated protein 1) is a protein of the KRAB protein family (Krüppel-associated box). These KRAB domain is a domain of repression which is encoded by many zinc finger protein-based transcription factors (KRAB zinc finger proteins or KRAP-ZFPs proteins).<ref>[1]</ref> | KAP-1 (KRAB – associated protein 1) is a protein of the KRAB protein family (Krüppel-associated box). These KRAB domain is a domain of repression which is encoded by many zinc finger protein-based transcription factors (KRAB zinc finger proteins or KRAP-ZFPs proteins).<ref>[1]Eishou Matsuda, Yasutoshi Agata, Manabu Sugai, Tomoya Katakai, Hiroyuki Gonda, and Akira Shimizu, Targeting of Krüppel-associated Box-containing Zinc Finger Proteins to Centromeric Heterochromatin, IMPLICATION FOR THE GENE SILENCING MECHANISMS, Received for publication, November 27, 2000, and in revised form, January 18, 2001 Published, JBC Papers in Press, January 19, 2001. </ref> | ||
KAP-1 is also known as Tripartite motif-containing 28 (TRIM28) and as transcriptional intermediary factor 1β (TIF1β). Indeed, KAP-1 is one of the TRIM proteins (wich code for TRIM genes). Among these TRIM proteins, there is the TIF1 family proteins, of which is part KAP-1 (that’s why KAP-1 is also known as TIF1β and TRIM28). <ref>[2]</ref> | KAP-1 is also known as Tripartite motif-containing 28 (TRIM28) and as transcriptional intermediary factor 1β (TIF1β). Indeed, KAP-1 is one of the TRIM proteins (wich code for TRIM genes). Among these TRIM proteins, there is the TIF1 family proteins, of which is part KAP-1 (that’s why KAP-1 is also known as TIF1β and TRIM28). <ref>[2]</ref> | ||
