Sandbox Reserved 1482: Difference between revisions
From Proteopedia
Jump to navigationJump to search
No edit summary |
No edit summary |
||
| Line 69: | Line 69: | ||
====Ligands==== | ====Ligands==== | ||
Alpha-D-mannose, calcium ion (Ca<sup>2+</sup>), copper ion (Cu<sup>2+</sup>) and N-acetl-D-glucosamine are the four ligands the factor VIII is able to bind to <sup>[2]</sup>. | Alpha-D-mannose, calcium ion (Ca<sup>2+</sup>), copper ion (Cu<sup>2+</sup>) and N-acetl-D-glucosamine are the four ligands the factor VIII is able to bind to <sup>[2]</sup>. | ||
In factor VIII there are two copper ions and their binding sites are located internally within the <scene name='80/802656/ | In factor VIII there are two copper ions and their binding sites are located internally within the <scene name='80/802656/A3cu/1'>A3</scene> and the <scene name='80/802656/A1/1'> A1 </scene> domain. In the latter, there is another ligand, a single calcium ion, bound to its binding site <sup>[9]</sup>. | ||
