Sandbox Reserved 1502: Difference between revisions
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The new experimental antirviral, here the (6-chloro-2-oxo-4-phenyl-1,2-dihydroquinolin-3-yl)acetic acid, interacts with the site with which <scene name='80/802676/Site_of_interaction/7'>the cofactor bind with the LEDGF/p75 cofactor</scene>. This site is situated in the core domain. | The new experimental antirviral, here the (6-chloro-2-oxo-4-phenyl-1,2-dihydroquinolin-3-yl)acetic acid, interacts with the site with which <scene name='80/802676/Site_of_interaction/7'>the cofactor bind with the LEDGF/p75 cofactor</scene>. This site is situated in the core domain. | ||
The molecule then inhibits the interaction between the LEDGF/p75 cofactor and the integrase. | The molecule then inhibits the interaction between the LEDGF/p75 cofactor and the integrase. | ||
The whole complex between the integrase and the cofactor is displyed on the proteopedia page [[ | The whole complex between the integrase and the cofactor is displyed on the proteopedia page [[2b4j]]. | ||
