Sandbox Reserved 1493: Difference between revisions
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{{Sandbox_Reserved_ESBS}}<!-- PLEASE ADD YOUR CONTENT BELOW HERE --> | {{Sandbox_Reserved_ESBS}}<!-- PLEASE ADD YOUR CONTENT BELOW HERE --> | ||
== Integrin αIIbβ3 (2VDL) == | == Integrin αIIbβ3 Headpiece (2VDL) == | ||
Integrin αIIbβ3 (or glycoprotein IIb/IIIa) is a complex present on the membrane of platelets that intervenes in the activation, adherence and aggregation of platelets during clotting. It is a cation-dependant heterodimeric transmembrane receptor containing a large extracellular headpiece and short intracellular tails. It is synthesized in megakaryocytes. | Integrin αIIbβ3 (or glycoprotein IIb/IIIa) is a complex present on the membrane of platelets that intervenes in the activation, adherence and aggregation of platelets during clotting. It is a cation-dependant heterodimeric transmembrane receptor containing a large extracellular headpiece and short intracellular tails. It is synthesized in megakaryocytes. | ||
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</StructureSection> | </StructureSection> | ||
== References == | == References == | ||
Structure and function: | |||
<ref group='xtra'>DOI: 10.1083/jcb.200801146</ref><ref group='xtra'>DOI: 10.1056/NEJM199506083322306</ref><ref group='xtra'>DOI: 10.1007/s00441-009-0834-6</ref><ref group='xtra'>DOI: 10.1074/jbc.M113.518126</ref><ref group='xtra'>DOI: 10.1016/S0735-1097(00)00979-7</ref><ref group='xtra'>DOI: 10.1074/jbc.M107021200</ref> | |||
<references group="xtra"/> | |||
Activity modulation: | Activity modulation: | ||
