6ixe: Difference between revisions

Line 1:

~~'''Unreleased structure'''~~

~~The entry~~ 6ixe is ~~ON HOLD~~ ~~until Paper Publication~~

==Crystal structure of SeMet apo SH3BP5 (I41)==

~~Authors~~:

== Structural highlights ==

<table><tr><td colspan='2'>[[6ixe]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6IXE OCA]. For a guided tour on the structure components use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6IXE FirstGlance].

~~Description~~:

</td></tr><tr id='ligand'><td class="sblockLbl">[[Ligand|Ligands:]]</td><td class="sblockDat"><scene name='pdbligand=SIN:SUCCINIC+ACID'>SIN</scene></td></tr>

[[Category: ~~Unreleased Structures~~]]

<tr id='NonStdRes'><td class="sblockLbl">[[Non-Standard_Residue|NonStd Res:]]</td><td class="sblockDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>

<tr id='resources'><td class="sblockLbl">Resources:</td><td class="sblockDat">[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6ixe FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6ixe OCA], [http://pdbe.org/6ixe PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6ixe RCSB], [http://www.ebi.ac.uk/pdbsum/6ixe PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6ixe ProSAT]</td></tr>

</table>

== Function ==

[[http://www.uniprot.org/uniprot/3BP5_HUMAN 3BP5_HUMAN]] Inhibits the auto- and transphosphorylation activity of BTK. Plays a negative regulatory role in BTK-related cytoplasmic signaling in B-cells. May be involved in BCR-induced apoptotic cell death.<ref>PMID:10339589</ref> <ref>PMID:9571151</ref>

== References ==

__TOC__

</StructureSection>

[[Category: Large Structures]]

[[Category: Fukai, S]]

[[Category: Goto-Ito, S]]

[[Category: Sato, Y]]

[[Category: Yamagata, A]]

[[Category: Gef]]

[[Category: Rab11]]

[[Category: Sh3bp5]]

[[Category: Signaling protein]]

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@@ Line 1: / Line 1: @@
-'''Unreleased structure'''
-The entry 6ixe is ON HOLD  until Paper Publication
+==Crystal structure of SeMet apo SH3BP5 (I41)==
+<StructureSection load='6ixe' size='340' side='right'caption='[[6ixe]], [[Resolution|resolution]] 3.35&Aring;' scene=''>
-Authors:
+== Structural highlights ==
+<table><tr><td colspan='2'>[[6ixe]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6IXE OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6IXE FirstGlance]. <br>
-Description:
+</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=SIN:SUCCINIC+ACID'>SIN</scene></td></tr>
-[[Category: Unreleased Structures]]
+<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6ixe FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6ixe OCA], [http://pdbe.org/6ixe PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6ixe RCSB], [http://www.ebi.ac.uk/pdbsum/6ixe PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6ixe ProSAT]</span></td></tr>
+</table>
+== Function ==
+[[http://www.uniprot.org/uniprot/3BP5_HUMAN 3BP5_HUMAN]] Inhibits the auto- and transphosphorylation activity of BTK. Plays a negative regulatory role in BTK-related cytoplasmic signaling in B-cells. May be involved in BCR-induced apoptotic cell death.<ref>PMID:10339589</ref> <ref>PMID:9571151</ref>
+== References ==
+<references/>
+__TOC__
+</StructureSection>
+[[Category: Large Structures]]
+[[Category: Fukai, S]]
+[[Category: Goto-Ito, S]]
+[[Category: Sato, Y]]
+[[Category: Yamagata, A]]
+[[Category: Gef]]
+[[Category: Rab11]]
+[[Category: Sh3bp5]]
+[[Category: Signaling protein]]