DNA polymerase: Difference between revisions
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Emily Bray (talk | contribs) Reorganized and added information, Fixed table Cori and I created. |
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====DNA Polymerase I==== | ====DNA Polymerase I==== | ||
[[DNA Polymerase I]] is a family A enzyme whose main function is excision repair of DNA strands through 3'-5' and 5'-3' exonuclease. This polymerase also helps with Okazaki fragment maturation. '''Okazaki fragments''' are short synthesized strands of DNA that form the lagging strand during DNA replication. When Polymerase I does replicate, it starts adding nucleotides at the RNA primer and moves in the 5'-3' direction. This polymerase is also the major polymerase in ''E. coli''.<ref name="ncbi" /> See also [[Taq DNA polymerase (Hebrew)]]. | [[DNA Polymerase I]] is a family A enzyme whose main function is excision repair of DNA strands through 3'-5' and 5'-3' exonuclease. This polymerase also helps with Okazaki fragment maturation. '''Okazaki fragments''' are short synthesized strands of DNA that form the lagging strand during DNA replication. When Polymerase I does replicate, it starts adding nucleotides at the RNA primer and moves in the 5'-3' direction. This polymerase is also the major polymerase in ''E. coli''.<ref name="ncbi" /> See also [[Taq DNA polymerase (Hebrew)]]. | ||
<scene name='44/440019/Cv/ | <scene name='44/440019/Cv/6'>Octylglucoside binding site</scene> in Family A DNA polymerase I ([[1taq]]). | ||
<scene name='44/440019/Cv/ | <scene name='44/440019/Cv/7'>Zn coordination site contains 3 Asp residues</scene> in Family A DNA polymerase I ([[1taq]]).<ref>PMID:7637814</ref> | ||
====DNA Polymerase II==== | ====DNA Polymerase II==== | ||