6j06: Difference between revisions

Line 1:

~~'''Unreleased structure'''~~

~~The entry~~ 6j06 ~~is ON HOLD until Paper Publication~~

==Crystal structure of intracellular B30.2 domain of BTN3A1 in complex with HMBPP-08==

~~Authors~~: ~~Yang, Y~~.Y., ~~Liu~~, W.D., ~~Cai, N~~.N., ~~Chen~~, C.C., ~~Guo, R~~.T., ~~Zhang, Y~~.H.

== Structural highlights ==

<table><tr><td colspan='2'>[[6j06]] is a 3 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6J06 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6J06 FirstGlance]. <br>

~~Description~~: ~~Crystal structure~~ of ~~intracellular B30~~.~~2 domain~~ of ~~BTN3A1 in complex with THZ~~-~~526~~

</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=99C:(2E)-3-(hydroxymethyl)-4-(4-methylphenyl)but-2-en-1-yl+trihydrogen+diphosphate'>99C</scene>, <scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=FLC:CITRATE+ANION'>FLC</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>

[[Category: ~~Unreleased~~ Structures]]

<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6j06 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6j06 OCA], [http://pdbe.org/6j06 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6j06 RCSB], [http://www.ebi.ac.uk/pdbsum/6j06 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6j06 ProSAT]</span></td></tr>

[[Category: Chen, C.C]]

</table>

[[Category: Liu, W.D]]

== Function ==

[[Category: ~~Zhang~~, Y.H]]

[[http://www.uniprot.org/uniprot/BT3A1_HUMAN BT3A1_HUMAN]] Plays a role in T-cell activation and in the adaptive immune response. Regulates the proliferation of activated T-cells. Regulates the release of cytokines and IFNG by activated T-cells. Mediates the response of T-cells toward infected and transformed cells that are characterized by high levels of phosphorylated metabolites, such as isopentenyl pyrophosphate.<ref>PMID:21113407</ref> <ref>PMID:21918970</ref> <ref>PMID:22767497</ref> <ref>PMID:22846996</ref>

[[Category: ~~Guo~~, ~~R.T~~]]

== References ==

[[Category: ~~Cai, N.N~~]]

[[Category: ~~Yang, Y.Y~~]]

__TOC__

</StructureSection>

[[Category: Large Structures]]

[[Category: Cai, N N]]

[[Category: Chen, C C]]

[[Category: Guo, R T]]

[[Category: Liu, W D]]

[[Category: Yang, Y Y]]

[[Category: Zhang, Y H]]

[[Category: Butyrophilin]]

[[Category: Signaling protein]]

Navigation menu

Page actions

Page actions

Personal tools

Navigation

Search

Tools

@@ Line 1: / Line 1: @@
-'''Unreleased structure'''
-The entry 6j06 is ON HOLD  until Paper Publication
+==Crystal structure of intracellular B30.2 domain of BTN3A1 in complex with HMBPP-08==
+<StructureSection load='6j06' size='340' side='right'caption='[[6j06]], [[Resolution|resolution]] 2.65&Aring;' scene=''>
-Authors: Yang, Y.Y., Liu, W.D., Cai, N.N., Chen, C.C., Guo, R.T., Zhang, Y.H.
+== Structural highlights ==
+<table><tr><td colspan='2'>[[6j06]] is a 3 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6J06 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6J06 FirstGlance]. <br>
-Description: Crystal structure of intracellular B30.2 domain of BTN3A1 in complex with THZ-526
+</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=99C:(2E)-3-(hydroxymethyl)-4-(4-methylphenyl)but-2-en-1-yl+trihydrogen+diphosphate'>99C</scene>, <scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=FLC:CITRATE+ANION'>FLC</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
-[[Category: Unreleased Structures]]
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6j06 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6j06 OCA], [http://pdbe.org/6j06 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6j06 RCSB], [http://www.ebi.ac.uk/pdbsum/6j06 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6j06 ProSAT]</span></td></tr>
-[[Category: Chen, C.C]]
+</table>
-[[Category: Liu, W.D]]
+== Function ==
-[[Category: Zhang, Y.H]]
+[[http://www.uniprot.org/uniprot/BT3A1_HUMAN BT3A1_HUMAN]] Plays a role in T-cell activation and in the adaptive immune response. Regulates the proliferation of activated T-cells. Regulates the release of cytokines and IFNG by activated T-cells. Mediates the response of T-cells toward infected and transformed cells that are characterized by high levels of phosphorylated metabolites, such as isopentenyl pyrophosphate.<ref>PMID:21113407</ref> <ref>PMID:21918970</ref> <ref>PMID:22767497</ref> <ref>PMID:22846996</ref>
-[[Category: Guo, R.T]]
+== References ==
-[[Category: Cai, N.N]]
+<references/>
-[[Category: Yang, Y.Y]]
+__TOC__
+</StructureSection>
+[[Category: Large Structures]]
+[[Category: Cai, N N]]
+[[Category: Chen, C C]]
+[[Category: Guo, R T]]
+[[Category: Liu, W D]]
+[[Category: Yang, Y Y]]
+[[Category: Zhang, Y H]]
+[[Category: Butyrophilin]]
+[[Category: Signaling protein]]