6npf: Difference between revisions

Line 1:

~~'''Unreleased structure'''~~

~~The entry~~ 6npf is ~~ON HOLD until Paper Publication~~

==Structure of E.coli enolase in complex with an analog of the natural product SF-2312 metabolite.==

~~Authors~~: ~~Erlandsen~~, H., ~~Krucinska~~, J., ~~Lombardo~~, M., ~~Wright, D~~.

== Structural highlights ==

<table><tr><td colspan='2'>[[6npf]] is a 6 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6NPF OCA]. For a guided tour on the structure components use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6NPF FirstGlance].

~~Description~~: ~~Structure~~ of E.~~coli enolase in complex with an analog~~ of ~~the natural product SF-2312 metabolite~~.

</td></tr><tr id='ligand'><td class="sblockLbl">[[Ligand|Ligands:]]</td><td class="sblockDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=KVM:[(3S)-1-hydroxy-2,5-dioxopyrrolidin-3-yl]phosphonic+acid'>KVM</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=TLA:L(+)-TARTARIC+ACID'>TLA</scene></td></tr>

[[Category: ~~Unreleased~~ Structures]]

<tr id='related'><td class="sblockLbl">[[Related_structure|Related:]]</td><td class="sblockDat">[[6d3q|6d3q]]</td></tr>

[[Category: ~~Wright, D~~]]

<tr id='activity'><td class="sblockLbl">Activity:</td><td class="sblockDat">[http://en.wikipedia.org/wiki/Phosphopyruvate_hydratase Phosphopyruvate hydratase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=4.2.1.11 4.2.1.11] </td></tr>

<tr id='resources'><td class="sblockLbl">Resources:</td><td class="sblockDat">[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6npf FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6npf OCA], [http://pdbe.org/6npf PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6npf RCSB], [http://www.ebi.ac.uk/pdbsum/6npf PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6npf ProSAT]</td></tr>

</table>

== Function ==

[[http://www.uniprot.org/uniprot/ENO_ECO45 ENO_ECO45]] Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis.

__TOC__

</StructureSection>

[[Category: Large Structures]]

[[Category: Phosphopyruvate hydratase]]

[[Category: Erlandsen, H]]

[[Category: Krucinska, J]]

[[Category: Lombardo, M]]

[[Category: Wright, D]]

[[Category: Complex]]

[[Category: Enolase]]

[[Category: Lyase]]

[[Category: Natural inhibitor]]

[[Category: Sf2312]]

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@@ Line 1: / Line 1: @@
-'''Unreleased structure'''
-The entry 6npf is ON HOLD  until Paper Publication
+==Structure of E.coli enolase in complex with an analog of the natural product SF-2312 metabolite.==
+<StructureSection load='6npf' size='340' side='right'caption='[[6npf]], [[Resolution|resolution]] 2.57&Aring;' scene=''>
-Authors: Erlandsen, H., Krucinska, J., Lombardo, M., Wright, D.
+== Structural highlights ==
+<table><tr><td colspan='2'>[[6npf]] is a 6 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6NPF OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6NPF FirstGlance]. <br>
-Description: Structure of E.coli enolase in complex with an analog of the natural product SF-2312 metabolite.
+</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=KVM:[(3S)-1-hydroxy-2,5-dioxopyrrolidin-3-yl]phosphonic+acid'>KVM</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=TLA:L(+)-TARTARIC+ACID'>TLA</scene></td></tr>
-[[Category: Unreleased Structures]]
+<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[6d3q|6d3q]]</td></tr>
-[[Category: Wright, D]]
+<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Phosphopyruvate_hydratase Phosphopyruvate hydratase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=4.2.1.11 4.2.1.11] </span></td></tr>
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6npf FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6npf OCA], [http://pdbe.org/6npf PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6npf RCSB], [http://www.ebi.ac.uk/pdbsum/6npf PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6npf ProSAT]</span></td></tr>
+</table>
+== Function ==
+[[http://www.uniprot.org/uniprot/ENO_ECO45 ENO_ECO45]] Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis.
+__TOC__
+</StructureSection>
+[[Category: Large Structures]]
+[[Category: Phosphopyruvate hydratase]]
 [[Category: Erlandsen, H]]
 [[Category: Krucinska, J]]
 [[Category: Lombardo, M]]
+[[Category: Wright, D]]
+[[Category: Complex]]
+[[Category: Enolase]]
+[[Category: Lyase]]
+[[Category: Natural inhibitor]]
+[[Category: Sf2312]]