6qgd: Difference between revisions

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'''Unreleased structure'''


The entry 6qgd is ON HOLD  until Paper Publication
==Structure of human Mcl-1 in complex with thienopyrimidine inhibitor==
 
<StructureSection load='6qgd' size='340' side='right'caption='[[6qgd]], [[Resolution|resolution]] 1.80&Aring;' scene=''>
Authors: Dokurno, P., Murray, J., Davidson, J., Chen, I., Davis, B., Graham, C.J., Harris, R., Jordan, A.M., Matassova, N., Pedder, C., Ray, S., Roughley, S., Smith, J., Walmsley, C., Wang, Y., Whitehead, N., Williamson, D.S., Casara, P., Le Diguarher, T., Hickman, J., Stark, J., Kotschy, A., Geneste, O., Hubbard, R.E.
== Structural highlights ==
 
<table><tr><td colspan='2'>[[6qgd]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6QGD OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6QGD FirstGlance]. <br>
Description: Structure of human Mcl-1 in complex with thienopyrimidine inhibitor
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=J1N:2-[(6-ethyl-5-phenyl-thieno[2,3-d]pyrimidin-4-yl)amino]-3-oxidanyl-propanoic+acid'>J1N</scene>, <scene name='pdbligand=MAL:MALTOSE'>MAL</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene></td></tr>
[[Category: Unreleased Structures]]
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[6qfi|6qfi]], [[6qfm|6qfm]], [[6qfq|6qfq]]</td></tr>
[[Category: Pedder, C]]
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6qgd FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6qgd OCA], [http://pdbe.org/6qgd PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6qgd RCSB], [http://www.ebi.ac.uk/pdbsum/6qgd PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6qgd ProSAT]</span></td></tr>
</table>
== Function ==
[[http://www.uniprot.org/uniprot/MALE_ECO57 MALE_ECO57]] Involved in the high-affinity maltose membrane transport system MalEFGK. Initial receptor for the active transport of and chemotaxis toward maltooligosaccharides (By similarity).
__TOC__
</StructureSection>
[[Category: Large Structures]]
[[Category: Casara, P]]
[[Category: Chen, I]]
[[Category: Chen, I]]
[[Category: Williamson, D.S]]
[[Category: Smith, J]]
[[Category: Le Diguarher, T]]
[[Category: Matassova, N]]
[[Category: Davidson, J]]
[[Category: Davidson, J]]
[[Category: Wang, Y]]
[[Category: Roughley, S]]
[[Category: Walmsley, C]]
[[Category: Graham, C.J]]
[[Category: Hubbard, R.E]]
[[Category: Davis, B]]
[[Category: Davis, B]]
[[Category: Diguarher, T Le]]
[[Category: Dokurno, P]]
[[Category: Geneste, O]]
[[Category: Graham, C J]]
[[Category: Harris, R]]
[[Category: Hickman, J]]
[[Category: Hickman, J]]
[[Category: Hubbard, R E]]
[[Category: Jordan, A M]]
[[Category: Kotschy, A]]
[[Category: Matassova, N]]
[[Category: Murray, J]]
[[Category: Pedder, C]]
[[Category: Ray, S]]
[[Category: Roughley, S]]
[[Category: Smith, J]]
[[Category: Stark, J]]
[[Category: Stark, J]]
[[Category: Walmsley, C]]
[[Category: Wang, Y]]
[[Category: Whitehead, N]]
[[Category: Whitehead, N]]
[[Category: Jordan, A.M]]
[[Category: Williamson, D S]]
[[Category: Harris, R]]
[[Category: Apoptosis]]
[[Category: Murray, J]]
[[Category: Mbp]]
[[Category: Dokurno, P]]
[[Category: Mcl1]]
[[Category: Kotschy, A]]
[[Category: Small molecule inhibitor]]
[[Category: Casara, P]]
[[Category: Geneste, O]]
[[Category: Ray, S]]

Revision as of 05:46, 12 June 2019

Structure of human Mcl-1 in complex with thienopyrimidine inhibitor

6qgd, resolution 1.80Å

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