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==Directed Evolution of Transaminases By Ancestral Reconstruction. Using Old Proteins for New Chemistries==
==Directed Evolution of Transaminases By Ancestral Reconstruction. Using Old Proteins for New Chemistries==
<StructureSection load='5kr3' size='340' side='right' caption='[[5kr3]], [[Resolution|resolution]] 1.95&Aring;' scene=''>
<StructureSection load='5kr3' size='340' side='right'caption='[[5kr3]], [[Resolution|resolution]] 1.95&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[5kr3]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/"chlorobacterium"_guillebeau_1890,_nom._rejic._opin._6_(not_"chlorobacterium"_lauterborn_1916) "chlorobacterium" guillebeau 1890, nom. rejic. opin. 6 (not "chlorobacterium" lauterborn 1916)]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5KR3 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5KR3 FirstGlance]. <br>
<table><tr><td colspan='2'>[[5kr3]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/"chlorobacterium"_guillebeau_1890,_nom._rejic._opin._6_(not_"chlorobacterium"_lauterborn_1916) "chlorobacterium" guillebeau 1890, nom. rejic. opin. 6 (not "chlorobacterium" lauterborn 1916)]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5KR3 OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=5KR3 FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=PLP:PYRIDOXAL-5-PHOSPHATE'>PLP</scene></td></tr>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=PLP:PYRIDOXAL-5-PHOSPHATE'>PLP</scene></td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[5kqt|5kqt]], [[5kqu|5kqu]], [[5kqv|5kqv]], [[5kr4|5kr4]], [[5kr5|5kr5]], [[5kr6|5kr6]]</td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[5kqt|5kqt]], [[5kqu|5kqu]], [[5kqv|5kqv]], [[5kr4|5kr4]], [[5kr5|5kr5]], [[5kr6|5kr6]]</td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Beta-alanine--pyruvate_transaminase Beta-alanine--pyruvate transaminase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.6.1.18 2.6.1.18] </span></td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Beta-alanine--pyruvate_transaminase Beta-alanine--pyruvate transaminase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.6.1.18 2.6.1.18] </span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5kr3 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5kr3 OCA], [http://pdbe.org/5kr3 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5kr3 RCSB], [http://www.ebi.ac.uk/pdbsum/5kr3 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5kr3 ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=5kr3 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5kr3 OCA], [http://pdbe.org/5kr3 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5kr3 RCSB], [http://www.ebi.ac.uk/pdbsum/5kr3 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5kr3 ProSAT]</span></td></tr>
</table>
</table>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Beta-alanine--pyruvate transaminase]]
[[Category: Beta-alanine--pyruvate transaminase]]
[[Category: Large Structures]]
[[Category: Newman, J]]
[[Category: Newman, J]]
[[Category: Peat, T S]]
[[Category: Peat, T S]]

Revision as of 08:27, 4 November 2020

Directed Evolution of Transaminases By Ancestral Reconstruction. Using Old Proteins for New Chemistries

5kr3, resolution 1.95Å

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