6nna: Difference between revisions

Line 1:

~~'''Unreleased structure'''~~

~~The entry~~ 6nna is ~~ON HOLD until Paper Publication~~

==Human Fatty Acid Synthase Psi/KR Tri-Domain with NADPH and Compound 22==

~~Authors~~: ~~Toms~~, A.V., ~~Martin~~, M.W.

== Structural highlights ==

<table><tr><td colspan='2'>[[6nna]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6NNA OCA]. For a guided tour on the structure components use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6NNA FirstGlance].

~~Description~~: ~~Human Fatty Acid Synthase Psi~~/~~KR Tri~~-~~Domain with NADPH and Compound 22~~

</td></tr><tr id='ligand'><td class="sblockLbl">[[Ligand|Ligands:]]</td><td class="sblockDat"><scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=KUA:{4-[4-(1,3-benzoxazol-2-yl)benzene-1-carbonyl]piperazin-1-yl}(1-hydroxycyclopropyl)methanone'>KUA</scene>, <scene name='pdbligand=NDP:NADPH+DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE+PHOSPHATE'>NDP</scene></td></tr>

[[~~Category~~: ~~Unreleased Structures~~]]

<tr id='NonStdRes'><td class="sblockLbl">[[Non-Standard_Residue|NonStd Res:]]</td><td class="sblockDat"><scene name='pdbligand=CAF:S-DIMETHYLARSINOYL-CYSTEINE'>CAF</scene></td></tr>

[[Category: Martin, M.W]]

<tr id='resources'><td class="sblockLbl">Resources:</td><td class="sblockDat">[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6nna FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6nna OCA], [http://pdbe.org/6nna PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6nna RCSB], [http://www.ebi.ac.uk/pdbsum/6nna PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6nna ProSAT]</td></tr>

[[Category: Toms, A.V]]

</table>

== Function ==

[[http://www.uniprot.org/uniprot/FAS_HUMAN FAS_HUMAN]] Fatty acid synthetase catalyzes the formation of long-chain fatty acids from acetyl-CoA, malonyl-CoA and NADPH. This multifunctional protein has 7 catalytic activities and an acyl carrier protein.

__TOC__

</StructureSection>

[[Category: Martin, M W]]

[[Category: Toms, A V]]

[[Category: Fatty acid synthase]]

[[Category: Human fa]]

[[Category: Keto-reductase]]

[[Category: Transferase]]

Navigation menu

Page actions

Page actions

Personal tools

Navigation

Search

Tools

@@ Line 1: / Line 1: @@
-'''Unreleased structure'''
-The entry 6nna is ON HOLD  until Paper Publication
+==Human Fatty Acid Synthase Psi/KR Tri-Domain with NADPH and Compound 22==
+<StructureSection load='6nna' size='340' side='right' caption='[[6nna]], [[Resolution|resolution]] 2.26&Aring;' scene=''>
-Authors: Toms, A.V., Martin, M.W.
+== Structural highlights ==
+<table><tr><td colspan='2'>[[6nna]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6NNA OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6NNA FirstGlance]. <br>
-Description: Human Fatty Acid Synthase Psi/KR Tri-Domain with NADPH and Compound 22
+</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=KUA:{4-[4-(1,3-benzoxazol-2-yl)benzene-1-carbonyl]piperazin-1-yl}(1-hydroxycyclopropyl)methanone'>KUA</scene>, <scene name='pdbligand=NDP:NADPH+DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE+PHOSPHATE'>NDP</scene></td></tr>
-[[Category: Unreleased Structures]]
+<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=CAF:S-DIMETHYLARSINOYL-CYSTEINE'>CAF</scene></td></tr>
-[[Category: Martin, M.W]]
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6nna FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6nna OCA], [http://pdbe.org/6nna PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6nna RCSB], [http://www.ebi.ac.uk/pdbsum/6nna PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6nna ProSAT]</span></td></tr>
-[[Category: Toms, A.V]]
+</table>
+== Function ==
+[[http://www.uniprot.org/uniprot/FAS_HUMAN FAS_HUMAN]] Fatty acid synthetase catalyzes the formation of long-chain fatty acids from acetyl-CoA, malonyl-CoA and NADPH. This multifunctional protein has 7 catalytic activities and an acyl carrier protein.
+__TOC__
+</StructureSection>
+[[Category: Martin, M W]]
+[[Category: Toms, A V]]
+[[Category: Fatty acid synthase]]
+[[Category: Human fa]]
+[[Category: Keto-reductase]]
+[[Category: Transferase]]