6nvb: Difference between revisions
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==Crystal structure of kallikrein-4== | |||
<StructureSection load='6nvb' size='340' side='right'caption='[[6nvb]], [[Resolution|resolution]] 1.64Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[6nvb]] is a 4 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6NVB OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6NVB FirstGlance]. <br> | |||
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr> | |||
[[Category: | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6nvb FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6nvb OCA], [http://pdbe.org/6nvb PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6nvb RCSB], [http://www.ebi.ac.uk/pdbsum/6nvb PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6nvb ProSAT]</span></td></tr> | ||
[[Category: Buckle, A | </table> | ||
[[Category: Riley, B | == Disease == | ||
[[Category: | [[http://www.uniprot.org/uniprot/KLK4_HUMAN KLK4_HUMAN]] Defects in KLK4 are the cause of amelogenesis imperfecta hypomaturation type 2A1 (AI2A1) [MIM:[http://omim.org/entry/204700 204700]]. AI2A1 is an autosomal recessive defect of enamel formation. The disorder involves both primary and secondary dentitions. The teeth have a shiny agar jelly appearance and the enamel is softer than normal. Brown pigment is present in middle layers of enamel.<ref>PMID:15235027</ref> | ||
== Function == | |||
[[http://www.uniprot.org/uniprot/KLK4_HUMAN KLK4_HUMAN]] Involved in enamel formation.<ref>PMID:15235027</ref> | |||
== References == | |||
<references/> | |||
__TOC__ | |||
</StructureSection> | |||
[[Category: Large Structures]] | |||
[[Category: Buckle, A M]] | |||
[[Category: McGowan, S]] | |||
[[Category: Riley, B T]] | |||
[[Category: Hydrolase]] | |||
[[Category: Klk4]] | |||
[[Category: Protease]] | |||
Revision as of 10:47, 17 July 2019
Crystal structure of kallikrein-4
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