6dfn: Difference between revisions
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==Crystal structure of estrogen receptor alpha in complex with receptor degrader 16aa== | ==Crystal structure of estrogen receptor alpha in complex with receptor degrader 16aa== | ||
<StructureSection load='6dfn' size='340' side='right' caption='[[6dfn]], [[Resolution|resolution]] 2.10Å' scene=''> | <StructureSection load='6dfn' size='340' side='right' caption='[[6dfn]], [[Resolution|resolution]] 2.10Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[6dfn]] is a 4 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6DFN OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6DFN FirstGlance]. <br> | <table><tr><td colspan='2'>[[6dfn]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6DFN OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6DFN FirstGlance]. <br> | ||
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=G91:(8S)-8-(4-{2-[3-(fluoromethyl)azetidin-1-yl]ethoxy}phenyl)-1,8-dihydro-2H-[1]benzopyrano[4,3-d][1]benzoxepine-5,11-diol'>G91</scene>, <scene name='pdbligand=G9J:(2S)-3-(3-hydroxyphenyl)-2-(4-iodophenyl)-4-methyl-2H-1-benzopyran-6-ol'>G9J</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=NI:NICKEL+(II)+ION'>NI</scene></td></tr> | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=G91:(8S)-8-(4-{2-[3-(fluoromethyl)azetidin-1-yl]ethoxy}phenyl)-1,8-dihydro-2H-[1]benzopyrano[4,3-d][1]benzoxepine-5,11-diol'>G91</scene>, <scene name='pdbligand=G9J:(2S)-3-(3-hydroxyphenyl)-2-(4-iodophenyl)-4-methyl-2H-1-benzopyran-6-ol'>G9J</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=NI:NICKEL+(II)+ION'>NI</scene></td></tr> | ||
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">ESR1, ESR, NR3A1 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr> | |||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6dfn FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6dfn OCA], [http://pdbe.org/6dfn PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6dfn RCSB], [http://www.ebi.ac.uk/pdbsum/6dfn PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6dfn ProSAT]</span></td></tr> | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6dfn FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6dfn OCA], [http://pdbe.org/6dfn PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6dfn RCSB], [http://www.ebi.ac.uk/pdbsum/6dfn PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6dfn ProSAT]</span></td></tr> | ||
</table> | </table> | ||
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__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
[[Category: Human]] | |||
[[Category: Kiefer, J R]] | [[Category: Kiefer, J R]] | ||
[[Category: Liang, J]] | [[Category: Liang, J]] | ||
