5oiz: Difference between revisions

From Proteopedia
Jump to navigationJump to search
← Older edit
OCA (talk | contribs)
Bots, Bureaucrats, journal, Administrators
3,331,613 edits
No edit summary
OCA (talk | contribs)
Bots, Bureaucrats, journal, Administrators
3,331,613 edits
No edit summary
 
Line 1: Line 1:


==Penicillin-Binding Protein 2X (PBP2X) from Streptococcus pneumoniae in complex with oxacillin==
==Penicillin-Binding Protein 2X (PBP2X) from Streptococcus pneumoniae in complex with oxacillin==
<StructureSection load='5oiz' size='340' side='right' caption='[[5oiz]], [[Resolution|resolution]] 2.70&Aring;' scene=''>
<StructureSection load='5oiz' size='340' side='right'caption='[[5oiz]], [[Resolution|resolution]] 2.70&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[5oiz]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Strr6 Strr6]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5OIZ OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5OIZ FirstGlance]. <br>
<table><tr><td colspan='2'>[[5oiz]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Streptococcus_pneumoniae_R6 Streptococcus pneumoniae R6]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5OIZ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5OIZ FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=1S6:(2R,4S)-5,5-DIMETHYL-2-[(1R)-1-{[(5-METHYL-3-PHENYL-1,2-OXAZOL-4-YL)CARBONYL]AMINO}-2-OXOETHYL]-1,3-THIAZOLIDINE-4-CARBOXYLIC+ACID'>1S6</scene></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.7&#8491;</td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">pbpX, spr0304 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=171101 STRR6])</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=1S6:(2R,4S)-5,5-DIMETHYL-2-[(1R)-1-{[(5-METHYL-3-PHENYL-1,2-OXAZOL-4-YL)CARBONYL]AMINO}-2-OXOETHYL]-1,3-THIAZOLIDINE-4-CARBOXYLIC+ACID'>1S6</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5oiz FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5oiz OCA], [http://pdbe.org/5oiz PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5oiz RCSB], [http://www.ebi.ac.uk/pdbsum/5oiz PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5oiz ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5oiz FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5oiz OCA], [https://pdbe.org/5oiz PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5oiz RCSB], [https://www.ebi.ac.uk/pdbsum/5oiz PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5oiz ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[http://www.uniprot.org/uniprot/PBPX_STRR6 PBPX_STRR6]] Penicillin-binding proteins (PBPs) function in the late steps of murein biosynthesis. Beta-lactams inactivate the PBPs by acylating an essential serine residue in the active site of these proteins.  
[https://www.uniprot.org/uniprot/PBPX_STRR6 PBPX_STRR6] Penicillin-binding proteins (PBPs) function in the late steps of murein biosynthesis. Beta-lactams inactivate the PBPs by acylating an essential serine residue in the active site of these proteins.
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
Line 19: Line 19:
</div>
</div>
<div class="pdbe-citations 5oiz" style="background-color:#fffaf0;"></div>
<div class="pdbe-citations 5oiz" style="background-color:#fffaf0;"></div>
==See Also==
*[[Penicillin-binding protein 3D structures|Penicillin-binding protein 3D structures]]
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Strr6]]
[[Category: Large Structures]]
[[Category: Bernardo-Garcia, N]]
[[Category: Streptococcus pneumoniae R6]]
[[Category: Hermoso, J A]]
[[Category: Bernardo-Garcia N]]
[[Category: Antibiotic]]
[[Category: Hermoso JA]]
[[Category: B-lactam]]
[[Category: Cell-wall]]
[[Category: Penicillin]]
[[Category: Transpeptidase]]
Retrieved from "https://proteopedia.org/5oiz"