DAHP synthase: Difference between revisions
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The DAHPS active site is located in a channel at the C-terminal of the enzyme where the <scene name='70/708806/Cv/7'>substrate (PEP)</scene>, <scene name='70/708806/Cv/8'>inhibitor (phenylalanine)</scene> and <scene name='70/708806/Cv/9'>metal ion (Mn+2)</scene> are seen. The bivalent metal is bound to a Cys-X-X-His motif.<ref>PMID:12126632</ref> | The DAHPS active site is located in a channel at the C-terminal of the enzyme where the <scene name='70/708806/Cv/7'>substrate (PEP)</scene>, <scene name='70/708806/Cv/8'>inhibitor (phenylalanine)</scene> and <scene name='70/708806/Cv/9'>metal ion (Mn+2)</scene> are seen. The bivalent metal is bound to a Cys-X-X-His motif.<ref>PMID:12126632</ref> | ||
== 3D Structures of DAHP synthase == | |||
[[DAHP synthase 3D structures]] | |||
</StructureSection> | </StructureSection> | ||
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**[[4ixx]] - NmDAHPS (mutant) + Mn <br /> | **[[4ixx]] - NmDAHPS (mutant) + Mn <br /> | ||
**[[3tqk]] - DAHPS + Mn – ''Francisella tularensis''<br /> | **[[3tqk]] - DAHPS + Mn – ''Francisella tularensis''<br /> | ||
**[[3nvt]] - LmDAHPS + Mn – ''Listeria monocytogenes''<br /> | |||
*DAHP synthase binary complex | *DAHP synthase binary complex | ||
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**[[2w19]] - MtDAHPS + chorismate mutase <br /> | **[[2w19]] - MtDAHPS + chorismate mutase <br /> | ||
**[[5huc]] - CgDAHPS + Mn + PEP – ''Corynebacterium glutamicum''<br /> | **[[5huc]] - CgDAHPS + Mn + PEP – ''Corynebacterium glutamicum''<br /> | ||
**[[3tfc]] - LmDAHPS + Mn + PEP <br /> | |||
*DAHP synthase higher complex | *DAHP synthase higher complex | ||
