3x3h: Difference between revisions

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==Crystal Structure of the Manihot esculenta Hydroxynitrile Lyase (MeHNL) 3KP (K176P, K199P, K224P) triple mutant==
==Crystal Structure of the Manihot esculenta Hydroxynitrile Lyase (MeHNL) 3KP (K176P, K199P, K224P) triple mutant==
<StructureSection load='3x3h' size='340' side='right' caption='[[3x3h]], [[Resolution|resolution]] 2.88&Aring;' scene=''>
<StructureSection load='3x3h' size='340' side='right'caption='[[3x3h]], [[Resolution|resolution]] 2.88&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[3x3h]] is a 8 chain structure with sequence from [http://en.wikipedia.org/wiki/Cassava Cassava]. This structure supersedes the now removed PDB entry [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=3rkt 3rkt]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3X3H OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3X3H FirstGlance]. <br>
<table><tr><td colspan='2'>[[3x3h]] is a 8 chain structure with sequence from [https://en.wikipedia.org/wiki/Cassava Cassava]. This structure supersedes the now removed PDB entry [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=3rkt 3rkt]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3X3H OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3X3H FirstGlance]. <br>
</td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">HNL ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=3983 Cassava])</td></tr>
</td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">HNL ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=3983 Cassava])</td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/(S)-hydroxynitrile_lyase (S)-hydroxynitrile lyase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=4.1.2.47 4.1.2.47] </span></td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[https://en.wikipedia.org/wiki/(S)-hydroxynitrile_lyase (S)-hydroxynitrile lyase], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=4.1.2.47 4.1.2.47] </span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3x3h FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3x3h OCA], [http://pdbe.org/3x3h PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3x3h RCSB], [http://www.ebi.ac.uk/pdbsum/3x3h PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=3x3h ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3x3h FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3x3h OCA], [https://pdbe.org/3x3h PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3x3h RCSB], [https://www.ebi.ac.uk/pdbsum/3x3h PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3x3h ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[http://www.uniprot.org/uniprot/HNL_MANES HNL_MANES]] Involved in cyanogenesis, the release of HCN from injured tissues. Decomposes a varieties of (R) or (S) cyanohydrins into HCN and the corresponding aldehydes and ketones. The natural substrate of this enzyme is (S)-acetone cyanohydrin.  
[[https://www.uniprot.org/uniprot/HNL_MANES HNL_MANES]] Involved in cyanogenesis, the release of HCN from injured tissues. Decomposes a varieties of (R) or (S) cyanohydrins into HCN and the corresponding aldehydes and ketones. The natural substrate of this enzyme is (S)-acetone cyanohydrin.  
__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Cassava]]
[[Category: Cassava]]
[[Category: Large Structures]]
[[Category: Asano, Y]]
[[Category: Asano, Y]]
[[Category: Cielo, C B.C]]
[[Category: Cielo, C B.C]]